Generic Name: ramipril (RA-mi-pril)
Brand Name: Altace
Ramipril capsules may cause injury or death to the fetus if taken during pregnancy. If you think you may be pregnant, contact your doctor right away. If you are planning to become pregnant, talk with your doctor about other treatment options.
Ramipril capsules is used for:
Treating high blood pressure alone or with other medicines. It is also used to decrease the risk of heart attack, stroke, and death in certain patients. It is also used to manage heart failure and improve survival after a heart attack. It may also be used for other conditions as determined by your doctor.
Ramipril capsules is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels. This helps to lower blood pressure.
Do NOT use ramipril capsules if:
- you are allergic to any ingredient in ramipril capsules or to another ACE inhibitor (eg, lisinopril)
- you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness) caused by treatment with an ACE inhibitor
- you are pregnant
- you are also taking aliskiren and you have either diabetes or kidney problems
- you are taking telmisartan
Contact your doctor or health care provider right away if any of these apply to you.
Before using ramipril capsules:
Some medical conditions may interact with ramipril capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of angioedema, including angioedema caused by treatment with an angiotensin receptor blocker (ARB) (eg, valsartan)
- if you have a history of heart problems (eg, aortic stenosis, heart failure), blood vessel problems, blood flow problems, bone marrow problems, diabetes, kidney problems (eg, renal artery stenosis), or liver problems (eg, ascites, cirrhosis)
- if you have a history of stroke, recent heart attack, or kidney transplant
- if you have an autoimmune disease (eg, rheumatoid arthritis, lupus, scleroderma)
- if you are dehydrated or have low blood volume, high blood potassium levels, or low blood sodium levels, or if you are on a low-salt (sodium) diet
- if you are receiving treatments to reduce sensitivity to bee stings
- if you are on dialysis or are scheduled to have surgery or receive anesthesia
Some MEDICINES MAY INTERACT with ramipril capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased
- Everolimus, sirolimus, or temsirolimus because the risk of angioedema may be increased
- Aliskiren or ARBs (eg, telmisartan) because the risk of certain side effects (eg, kidney problems, high blood potassium levels, low blood pressure) may be increased
- Eplerenone, potassium-sparing diuretics (eg, spironolactone, triamterene), potassium supplements, or trimethoprim because the risk of high blood potassium levels may be increased
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen, indomethacin) because they may decrease ramipril capsules's effectiveness and the risk of serious kidney problems may be increased
- Insulin or other oral diabetes medicines (eg, glyburide, metformin) because the risk of low blood sugar may be increased
- Certain gold-containing medicines (eg, sodium aurothiomalate) because flushing, nausea, vomiting, and low blood pressure may occur
- Lithium or thiopurines (eg, azathioprine) because the risk of their side effects may be increased by ramipril capsules
This may not be a complete list of all interactions that may occur. Ask your health care provider if ramipril capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use ramipril capsules:
Use ramipril capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take ramipril capsules by mouth with or without food.
- Ramipril capsules should usually be swallowed whole. If you have difficulty swallowing the capsule, it can be opened and the contents sprinkled on a small amount (about 4 oz) of applesauce or mixed in a half glass (4 oz/120 mL) of water or apple juice. It is best to eat or drink the entire mixture immediately after mixing. The mixture may be stored at room temperature for up to 24 hours or in the refrigerator for up to 48 hours.
- Continue to take ramipril capsules even if you feel well. Do not miss any doses.
- If you miss a dose of ramipril capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use ramipril capsules.
Important safety information:
- Ramipril capsules may cause dizziness, light-headedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use ramipril capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Ramipril capsules may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Ramipril capsules may cause a serious side effect called angioedema. The risk may be higher in black patients. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
- Ramipril capsules may not work as well in black patients. Contact your doctor if your symptoms do not improve or if they become worse.
- Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.
- Ramipril capsules may cause a dry, unproductive cough. If caused by ramipril capsules, this symptom usually stops after treatment with ramipril capsules is stopped.
- Rarely, ramipril capsules may lower the ability of your body to fight infection. This risk may be greater if you have certain other health problems (eg, kidney problems, collagen vascular disease). Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- Check with your doctor before you use a salt substitute or a product that has potassium in it.
- Tell your doctor or dentist that you take ramipril capsules before you receive any medical or dental care, emergency care, or surgery.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
- If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
- Diabetes patients - Ramipril capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Lab tests, including blood pressure, blood potassium levels, and kidney function, may be performed while you use ramipril capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use ramipril capsules with caution in the ELDERLY; they may be more sensitive to its effects.
- Ramipril capsules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY AND BREAST-FEEDING: Ramipril capsules may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if ramipril capsules is found in breast milk. Do not breast-feed while taking ramipril capsules.
Possible side effects of ramipril capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Cough; dizziness; headache; tiredness.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the hands, eyes, mouth, face, lips, throat, or tongue; hoarseness); chest pain; decreased urination; irregular heartbeat; mental or mood changes; red, swollen, blistered, or peeling skin; seizures; shortness of breath; stomach or back pain (with or without nausea or vomiting); symptoms of infection (eg, fever, chills, persistent sore throat); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, stomach pain, yellowing of the skin or eyes); symptoms of low blood pressure (eg, fainting, severe dizziness, light-headedness); unusual bruising or bleeding; unusual swelling; unusual tiredness or weakness; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; severe dizziness or light-headedness.Proper storage of ramipril capsules:
Store ramipril capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep ramipril capsules out of the reach of children and away from pets.
- If you have any questions about ramipril capsules, please talk with your doctor, pharmacist, or other health care provider.
- Ramipril capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take ramipril capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ramipril capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ramipril capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using ramipril capsules.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about ramipril
- Other brands: Altace