Prilosec OTC delayed-release capsules and tablets

Pronunciation

Generic Name: omeprazole magnesium (oh-MEP-ra-zole mag-NEE-zee-um)
Brand Name: Prilosec OTC

Prilosec OTC delayed-release capsules and tablets is used for:

Treating frequent (2 or more days per week) heartburn. It may also be used for other conditions as determined by your doctor.

Prilosec OTC delayed-release capsules and tablets is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach.

Do NOT use Prilosec OTC delayed-release capsules and tablets if:

  • you are allergic to any ingredient in Prilosec OTC delayed-release capsules and tablets or to any other PPI (eg, esomeprazole)
  • you have black or bloody stools, trouble or pain when swallowing, or you are vomiting blood
  • you are taking clopidogrel, dasatinib, certain HIV protease inhibitors (eg, atazanavir, nelfinavir), rifampin, rilpivirine, or St. John's wort

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

Before using Prilosec OTC delayed-release capsules and tablets:

Some medical conditions may interact with Prilosec OTC delayed-release capsules and tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have low blood potassium or magnesium levels, liver problems, or stomach or bowel cancer
  • if you have nausea or vomiting; stomach pain; heartburn with light-headedness, sweating, or dizziness; chest or shoulder pain with shortness of breath; unusual sweating; pain spreading to the arms, neck, or shoulders; or light-headedness
  • if you have unexplained weight loss; frequent chest pain; or frequent wheezing, especially along with heartburn
  • if you have had heartburn for more than 3 months
  • if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)

Some MEDICINES MAY INTERACT with Prilosec OTC delayed-release capsules and tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
  • Voriconazole because it may increase the risk of Prilosec OTC delayed-release capsules and tablets's side effects
  • Ginkgo biloba, rifampin, or St. John's wort because they may decrease Prilosec OTC delayed-release capsules and tablets's effectiveness
  • Anticoagulants (eg, warfarin), benzodiazepines (eg, diazepam), cilostazol, citalopram, cyclosporine, digoxin, disulfiram, escitalopram, hydantoins (eg, phenytoin), methotrexate, saquinavir, or tacrolimus because the risk of their side effects may be increased by Prilosec OTC delayed-release capsules and tablets
  • Ampicillins, azole antifungals (eg, ketoconazole), clopidogrel, certain HIV protease inhibitors (eg, atazanavir, nelfinavir), iron, mycophenolate, rilpivirine, or tyrosine kinase inhibitors (eg, dasatinib, erlotinib) because their effectiveness may be decreased by Prilosec OTC delayed-release capsules and tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prilosec OTC delayed-release capsules and tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prilosec OTC delayed-release capsules and tablets:

Use Prilosec OTC delayed-release capsules and tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Prilosec OTC delayed-release capsules and tablets by mouth on an empty stomach before eating breakfast.
  • Take Prilosec OTC delayed-release capsules and tablets with a full glass of water (8 oz/240 mL).
  • Swallow Prilosec OTC delayed-release capsules and tablets whole. Do not break, crush, or chew before swallowing.
  • You may take antacids while you are using Prilosec OTC delayed-release capsules and tablets if you are directed to do so by your doctor.
  • You may take a 14-day course of Prilosec OTC delayed-release capsules and tablets once every 4 months. Do NOT take Prilosec OTC delayed-release capsules and tablets for longer than 14 days or take more than 1 course every 4 months without first checking with your doctor.
  • If you miss a dose of Prilosec OTC delayed-release capsules and tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prilosec OTC delayed-release capsules and tablets.

Important safety information:

  • Prilosec OTC delayed-release capsules and tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Prilosec OTC delayed-release capsules and tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Prilosec OTC delayed-release capsules and tablets may take 1 to 4 days to reach its full effect. Do NOT take more than the recommended dose or use for longer than 14 days without checking with your doctor.
  • Check with your doctor if your heartburn does not get better or if it gets worse. Check with your doctor if you need to take Prilosec OTC delayed-release capsules and tablets for more than 14 days or if you need to take more than 1 course of treatment every 4 months.
  • Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
  • Prilosec OTC delayed-release capsules and tablets may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you use Prilosec OTC delayed-release capsules and tablets in high doses, for longer than a year, or if you are older than 50 years old. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Contact your doctor if you have any questions about this information.
  • Low blood magnesium levels have been reported rarely in patients taking PPIs for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking Prilosec OTC delayed-release capsules and tablets for a long time, or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
  • Check with your doctor to see whether you should take a calcium and vitamin D supplement while you take Prilosec OTC delayed-release capsules and tablets.
  • Prilosec OTC delayed-release capsules and tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Prilosec OTC delayed-release capsules and tablets.
  • Prilosec OTC delayed-release capsules and tablets should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
  • Use Prilosec OTC delayed-release capsules and tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
  • Prilosec OTC delayed-release capsules and tablets should not be used in CHILDREN younger than 18 years old without first checking with their doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Prilosec OTC delayed-release capsules and tablets while you are pregnant. Prilosec OTC delayed-release capsules and tablets is found in breast milk. Do not breast-feed while taking Prilosec OTC delayed-release capsules and tablets.

Possible side effects of Prilosec OTC delayed-release capsules and tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; gas; headache; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; bone pain; change in the amount of urine produced; chest pain; dark urine; fast, slow, or irregular heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; severe diarrhea; severe stomach pain or cramps; swelling of the hands, ankles, or feet; unusual bruising or bleeding; unusual tiredness; vision changes; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; dry mouth; fast heartbeat; flushing; increased sweating; severe headache, drowsiness, or nausea; vomiting.

Proper storage of Prilosec OTC delayed-release capsules and tablets:

Store Prilosec OTC delayed-release capsules and tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Prilosec OTC delayed-release capsules and tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Prilosec OTC delayed-release capsules and tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Prilosec OTC delayed-release capsules and tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Prilosec OTC delayed-release capsules and tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Prilosec OTC delayed-release capsules and tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Prilosec OTC delayed-release capsules and tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Prilosec OTC delayed-release capsules and tablets.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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