PreNexa

Generic Name: prenatal multivitamin without vitamin a with minerals, iron, folic acid, docusate sodium, and dha (pree-NATE-al MUL-tee-VYE-ta-mins/VYE-ta-min A/MIN-er-als/EYE-urn/FOE-lik AS-id/DOK-ue-sate SOE-dee-um)
Brand Name: Examples include PreNexa and Taron-Prex

Accidental overdose of products that contain iron is a leading cause of fatal poisoning in children younger than 6 years old. Keep this and all medicines out of the reach of children. In case of accidental ingestion, call your local poison control center or your doctor at once.


PreNexa is used for:

Treating or preventing a lack of vitamins or minerals before, during, and after pregnancy and while breast-feeding. It may also be used for other conditions as determined by your doctor.

PreNexa is a vitamin, mineral, iron, folic acid, docosahexaenoic acid (DHA), and stool softener combination. It works by providing vitamins and minerals to the body to help meet nutritional requirements. The stool softener helps prevent constipation that may occur with iron products.

Do NOT use PreNexa if:

  • you are allergic to any ingredient in PreNexa, including soy, fish, or fish oil
  • you have hemochromatosis (a disorder of iron metabolism)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

Before using PreNexa:

Some medical conditions may interact with PreNexa. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have stomach or intestinal problems (eg, colitis, Crohn disease, diverticulitis, peptic ulcer), blood problems (eg, pernicious anemia, other types of anemia, porphyria), bleeding problems (eg, hemophilia), or a history of kidney stones
  • if you have had multiple blood transfusions
  • if you are taking mineral oil

Some MEDICINES MAY INTERACT with PreNexa. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Oral anticoagulants (eg, warfarin) because the risk of bleeding may be increased by PreNexa
  • Fluorouracil because its actions and the risk of its side effects may be increased by PreNexa
  • Hydantoins (eg, phenytoin), methyldopa, or penicillamine because their effectiveness may be decreased by PreNexa

This may not be a complete list of all interactions that may occur. Ask your health care provider if PreNexa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use PreNexa:

Use PreNexa as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take PreNexa by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Take PreNexa by mouth with a full glass of water (8 oz/240 mL).
  • Do not take an antacid within 1 hour before or 2 hours after you take PreNexa.
  • Avoid taking PreNexa with dairy products; they may interfere with the absorption of the iron in PreNexa.
  • Many medicines (eg, used for infection, blood pressure, low blood platelets, osteoporosis, thyroid problems) should not be taken at the same time as PreNexa; their effectiveness may be decreased. Ask your doctor or pharmacist if your dose of PreNexa should be separated from your dose of any of your other medicines.
  • If you miss a dose of PreNexa, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use PreNexa.

Important safety information:

  • PreNexa may discolor the stools. This is normal and not a cause for concern.
  • PreNexa has iron in it. Iron overdose is a leading cause of fatal poisoning in children younger than 6 years old. In case of an overdose, call a doctor or poison control center right away.
  • PreNexa has pyridoxine (vitamin B6) in it. Before you start any new medicine, check the label to see if it has pyridoxine (vitamin B6) in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Some brands of PreNexa may contain fish oil or soy. If you have had an allergic reaction to fish, fish oil, or soy, ask your pharmacist if your brand contains fish oil.
  • This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.
  • Do not take large doses of vitamins while you use PreNexa unless your doctor tells you to.
  • PREGNANCY and BREAST-FEEDING: PreNexa is intended for use during pregnancy and breast-feeding. If you are or will be breast-feeding while you use PreNexa, check with your doctor.

Possible side effects of PreNexa:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dark or discolored stools; diarrhea; nausea; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stools; stomach pain or cramping.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include black, tarry stools; chest pain; lack of feeling alert; loss of balance; seizure; severe nausea, vomiting, diarrhea, or stomach pain; shortness of breath; sluggishness; trouble breathing; unusual tiredness or weakness; unusually pale skin; weak pulse.

Proper storage of PreNexa:

Store PreNexa at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep PreNexa out of the reach of children and away from pets.

General information:

  • If you have any questions about PreNexa, please talk with your doctor, pharmacist, or other health care provider.
  • PreNexa is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take PreNexa or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about PreNexa. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to PreNexa. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using PreNexa.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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