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Prednisolone acetate suspension

Pronunciation

Generic Name: prednisolone acetate (pred-NIS-oh-lone AS-e-tate)
Brand Name: Flo-Pred

Prednisolone acetate suspension is used for:

Treating certain types of allergies, arthritis, autoimmune diseases, blood disorders, bowel problems, cancer, endocrine problems, eye problems, kidney problems, lung or breathing problems, nervous system problems, or skin conditions. It is also used to treat conditions related to organ transplants or certain infections. It may also be used for other conditions as determined by your doctor.

Prednisolone acetate suspension is a corticosteroid. It works by modifying the body's immune response to various conditions and decreasing inflammation.

Do NOT use prednisolone acetate suspension if:

  • you are allergic to any ingredient in prednisolone acetate suspension or to other corticosteroids (eg, methylprednisolone)
  • you have a systemic fungal infection, a malaria infection in the brain, inflammation of the optic nerve (optic neuritis), or herpes infection of the eye
  • you are scheduled to have a live or attenuated live vaccination (eg, smallpox)
  • you are taking mifepristone

Contact your doctor or health care provider right away if any of these apply to you.

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Before using prednisolone acetate suspension:

Some medical conditions may interact with prednisolone acetate suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of adrenal gland problems, diabetes, eye problems (eg, cataracts, glaucoma, infection), heart problems (eg, congestive heart failure), a recent heart attack, high blood pressure, kidney problems, liver problems, mental or mood problems (eg, depression), seizures, swelling or fluid retention (edema), or thyroid problems
  • if you have or have recently had a fungal, bacterial, viral, or other type of infection; herpes infection of the eye; chickenpox; measles; or shingles
  • if you have HIV infection or tuberculosis (TB) infection, or if you have had ever had a positive TB skin test
  • if you have any stomach problems (eg, ulcers), bowel problems (eg, blockage, perforation, or infection; unexplained diarrhea; diverticulitis; ulcerative colitis), recent bowel surgery, or inflammation of the esophagus
  • if you have trouble sleeping, muscle problems (eg, myasthenia gravis), or weak bones (eg, osteoporosis) or a risk of osteoporosis (eg, family history of osteoporosis)
  • if you have had a recent vaccination (eg, smallpox)

Some MEDICINES MAY INTERACT with prednisolone acetate suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Amphotericin B, cyclosporine, estrogens (eg, estradiol), oral contraceptives (birth control pills), ketoconazole, macrolide antibiotics (eg, clarithromycin), or tacrolimus because they may increase the risk of prednisolone acetate suspension's side effects
  • Aminoglutethimide, barbiturates (eg, phenobarbital), carbamazepine, cholestyramine, hydantoins (eg, phenytoin), or rifamycins (eg, rifampin) because they may decrease prednisolone acetate suspension's effectiveness
  • Anticholinesterases (eg, pyridostigmine), digoxin, certain diuretics (eg, furosemide, hydrochlorothiazide), live or attenuated live vaccines (eg, smallpox), methotrexate, mifepristone, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), quinolone antibiotics (eg, ciprofloxacin), ritodrine, or salicylates (eg, aspirin) because the risk of their side effects may be increased by prednisolone acetate suspension
  • Anticoagulants (eg, warfarin), insulin or other diabetes medicines, interleukin-2 (eg, aldesleukin), isoniazid, or killed or inactivated vaccines because their effectiveness may be decreased by prednisolone acetate suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if prednisolone acetate suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use prednisolone acetate suspension:

Use prednisolone acetate suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take prednisolone acetate suspension by mouth with food.
  • Read the instructions for use before you start using prednisolone acetate suspension and each time you get a refill. Only use the syringe that is provided with prednisolone acetate suspension to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Shake well before each use.
  • Follow the instructions for cleaning the syringe after each use.
  • If you miss a dose of prednisolone acetate suspension, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use prednisolone acetate suspension.

Important safety information:

  • Prednisolone acetate suspension may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does. Contact your doctor if you are exposed to chickenpox or measles.
  • Report to your doctor any injuries or signs of infection (fever, chills, sore throat, pain during urination, or muscle aches) for up to 12 months after stopping prednisolone acetate suspension.
  • Carry an ID card at all times that says you take prednisolone acetate suspension.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking prednisolone acetate suspension. Talk with your doctor before you receive any vaccine.
  • Tell your doctor or dentist that you take prednisolone acetate suspension before you receive any medical or dental care, emergency care, or surgery.
  • Prednisolone acetate suspension may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Prednisolone acetate suspension may cause an increase in blood pressure, salt and water retention, and increased potassium loss. It may be necessary to restrict the use of salt in your diet and take a potassium supplement if instructed to do so by your doctor. Discuss any questions or concerns with your doctor.
  • Prednisolone acetate suspension can cause a decrease in the amount of calcium in your bones and increase the risk of osteoporosis. Talk with doctor about taking calcium and vitamin D while you are taking prednisolone acetate suspension.
  • Prednisolone acetate suspension may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking prednisolone acetate suspension for a few days before the tests.
  • Lab tests, including adrenal function, blood glucose levels, blood potassium and sodium levels, blood pressure monitoring, weight checks, chest x-rays, and eye pressure, may be performed while you use prednisolone acetate suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Caution is advised when using prednisolone acetate suspension in CHILDREN; they may be more sensitive to its effects.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take prednisolone acetate suspension.
  • PREGNANCY and BREAST-FEEDING: Prednisolone acetate suspension may cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using prednisolone acetate suspension while you are pregnant. Prednisolone acetate suspension is found in breast milk. If you are or will be breast-feeding while you use prednisolone acetate suspension, check with your doctor. Discuss any possible risks to your baby.

If you are on long-term or high-dosage therapy and you suddenly stop taking prednisolone acetate suspension, you may have WITHDRAWAL symptoms, including fever, vomiting, appetite loss, diarrhea, nausea, dizziness, weight loss, weakness, general body discomfort, or joint or muscle pain. If you need to stop prednisolone acetate suspension, your doctor will gradually lower your dose.

Possible side effects of prednisolone acetate suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; dizziness; facial flushing; headache; increased appetite; increased sweating; mild swelling; nausea; nervousness; trouble sleeping; upset stomach; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); black, tarry stools; burning, numbness, or tingling; calf or leg pain, swelling, redness, or tenderness; changes in body fat; changes in menstrual period; changes in skin color; chest pain; easy bruising or bleeding; fainting; fast, slow, or irregular heartbeat; mental or mood changes (eg, depression); muscle pain, cramps, weakness, or wasting; numbness of an arm or leg; persistent trouble sleeping; seizures; severe or persistent dizziness or headache; severe or persistent nausea, vomiting, or stomach or back pain; severe or persistent swelling of the hands, arms, feet, or legs; shortness of breath; symptoms of infection (eg, fever, chills, persistent sore throat); tendon or bone pain; thinning of skin; unusual weight gain; vision changes or other eye problems; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of prednisolone acetate suspension:

Store prednisolone acetate suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Do not refrigerate. Keep in the original container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep prednisolone acetate suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about prednisolone acetate suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Prednisolone acetate suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take prednisolone acetate suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about prednisolone acetate suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to prednisolone acetate suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using prednisolone acetate suspension.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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