Phoslyra solution

Generic Name: calcium acetate (KAL-see-um AS-e-tate)
Brand Name: Phoslyra

Phoslyra solution is used for:

Reducing phosphate levels in late-stage kidney failure.

Phoslyra solution is a phosphate binder. It works by preventing phosphate in the stomach and intestines from being absorbed into the body.

Do NOT use Phoslyra solution if:

  • you are allergic to any ingredient in Phoslyra solution
  • you have high blood calcium levels (hypercalcemia)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Phoslyra solution:

Some medical conditions may interact with Phoslyra solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have low phosphate levels
  • if you are taking medicine for seizures or irregular heartbeat

Some MEDICINES MAY INTERACT with Phoslyra solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin because the risk of side effects such as irregular heartbeat may be increased
  • Any product (eg, certain nutritional supplements) that contains maltitol because the risk of diarrhea may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Phoslyra solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Phoslyra solution:

Use Phoslyra solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Phoslyra solution with meals.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Do not take Phoslyra solution at the same time as a bisphosphonate (eg, alendronate), eltrombopag, estramustine, a quinolone (eg, ciprofloxacin), a tetracycline (eg, doxycycline), or a thyroid hormone (eg, levothyroxine). Talk to your doctor or pharmacist about how to separate these medicines from your dose of Phoslyra solution.
  • If you miss a dose of Phoslyra solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Phoslyra solution.

Important safety information:

  • Be sure to follow the diet plan prescribed by your health care provider.
  • Do not take any other medicines containing calcium (eg, calcium supplements, certain antacids, multivitamins containing calcium) while you are taking Phoslyra solution.
  • Lab tests, including calcium and blood phosphate levels, may be performed while you take Phoslyra solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Phoslyra solution with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Phoslyra solution while you are pregnant. Phoslyra solution is found in breast milk. If you are or will be breast-feeding while you are taking Phoslyra solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Phoslyra solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; constipation; fast, slow, or irregular heartbeat; increased thirst or urination; loss of appetite; loss of consciousness; mental or mood changes; muscle weakness; severe or persistent nausea; sluggishness; unusual tiredness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; constipation; fast, slow, or irregular heartbeat; loss of appetite; loss of consciousness; mental or mood changes; muscle weakness; severe or persistent nausea; sluggishness; vomiting.

Proper storage of Phoslyra solution:

Store Phoslyra solution at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Phoslyra solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Phoslyra solution, please talk with your doctor, pharmacist, or other health care provider.
  • Phoslyra solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Phoslyra solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Phoslyra solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Phoslyra solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Phoslyra solution.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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