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Generic Name: famotidine (fa-MOE-tih-deen)
Brand Name: Examples include Pepcid and Pepcid AC

Pepcid is used for:

Treating and preventing ulcers and treating and preventing heartburn associated with acid indigestion and sour stomach. It is also used to treat gastroesophageal reflux disease (GERD), conditions that cause increased acid secretion (eg, Zollinger-Ellison syndrome), and esophagitis. It also may be used for other conditions as determined by your doctor.

Pepcid is an H2 (histamine) blocker. It reduces stomach acid by blocking one of the chemicals (histamine) that stimulates the release of acid into the stomach.

Do NOT use Pepcid if:

  • you are allergic to any ingredient in Pepcid or to other H2 blockers (eg, ranitidine)
  • you are taking dasatinib

Contact your doctor or health care provider right away if any of these apply to you.

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Always get your pet's drug and dose recommendation from the veterinarian.

Before using Pepcid:

Some medical conditions may interact with Pepcid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney or liver problems
  • if you have trouble swallowing, pain swallowing food, vomiting with blood or vomit that looks like coffee grounds, or bloody or black stools
  • if you have frequent chest pain, unexplained weight loss, nausea or vomiting, or stomach pain
  • if you have had heartburn for longer than 3 months; heartburn associated with light-headedness, sweating, or dizziness; or frequent wheezing, especially with heartburn
  • if you have chest, arm, neck, or shoulder pain, especially with shortness of breath; sweating; or light-headedness

Some MEDICINES MAY INTERACT with Pepcid. Tell your health care provider if you are taking any other medicines, especially any of the following: Dasatinib because its effectiveness may be decreased by Pepcid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pepcid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pepcid:

Use Pepcid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Pepcid by mouth with or without food.
  • Take Pepcid by mouth with a full glass of water (8 oz/240 mL).
  • If you take atazanavir, erlotinib, itraconazole, ketoconazole, or rilpivirine, ask your doctor or pharmacist how to take it with Pepcid.
  • Ask your doctor before taking antacids or other acid reducers with Pepcid.
  • If you miss a dose of Pepcid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pepcid.

Important safety information:

  • Pepcid may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Pepcid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If your symptoms do not get better or if they get worse, check with your doctor.
  • If you are taking a nonprescription form of Pepcid and you need to take it for more than 14 days for heartburn symptoms, stop use and contact your doctor.
  • You may need to make significant diet and lifestyle changes to help treat and prevent ulcers and other digestive problems, including stress-reduction programs, exercise, and diet changes. Discuss any questions or concerns with your doctor.
  • Use Pepcid with caution in the ELDERLY; they may be more sensitive to its effects.
  • Use of nonprescription forms of Pepcid is not recommended in CHILDREN younger than 12 years old without first talking with the child's doctor.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pepcid while you are pregnant. Pepcid is found in breast milk. Do not breast-feed while taking Pepcid.

Possible side effects of Pepcid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); irregular heartbeat; seizures.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Pepcid:

Store Pepcid between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pepcid out of the reach of children and away from pets.

General information:

  • If you have any questions about Pepcid, please talk with your doctor, pharmacist, or other health care provider.
  • Pepcid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Pepcid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Pepcid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Pepcid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Pepcid.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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