Pentosan

Generic Name: pentosan (PEN-toe-san)
Brand Name: Elmiron

Pentosan is used for:

Relieving bladder pain or discomfort caused by bladder inflammation.

Pentosan is an interstitial cystitis agent. The exact way it works is not known, but it is thought to protect the bladder wall while it heals.

Do NOT use pentosan if:

  • you are allergic to any ingredient in pentosan

Contact your doctor or health care provider right away if any of these apply to you.

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Before using pentosan:

Some medical conditions may interact with pentosan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have or have a history of a bleeding disorder due to low platelet levels, bleeding in the brain, hemophilia, stomach ulcers, intestinal polyps, or diverticulitis
  • if you have liver problems or blood-clotting problems, or you are scheduled for surgery or another medical procedure

Some MEDICINES MAY INTERACT with pentosan. Tell your health care provider if you are taking any medicines, especially any of the following:

  • Anticoagulants (eg, heparin, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if pentosan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pentosan:

Use pentosan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pentosan comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get pentosan refilled.
  • Take pentosan by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
  • Take pentosan with a full glass of water (8 oz/240 mL).
  • Continue to take pentosan even if you feel well. Do not miss any doses.
  • If you miss a dose of pentosan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pentosan.

Important safety information:

  • Pentosan may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use pentosan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • It may take 3 to 6 months for pentosan to reach its full effect. Do not stop taking pentosan or take more than the recommended dose without checking with your doctor.
  • Pentosan may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Tell your doctor or dentist that you take pentosan before you receive any medical or dental care, emergency care, or surgery.
  • Pentosan should not be used in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pentosan while you are pregnant. It is not known if pentosan is found in breast milk. If you are or will be breast-feeding while you use pentosan, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of pentosan:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; hair loss; headache; nausea; stomach upset; swelling of fingers, hands, toes, or feet.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; unusual bruising or bleeding; vomiting that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of pentosan:

Store pentosan at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pentosan out of the reach of children and away from pets.

General information:

  • If you have any questions about pentosan, please talk with your doctor, pharmacist, or other health care provider.
  • Pentosan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pentosan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pentosan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pentosan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pentosan.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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