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Pannaz S syrup

Generic Name: carbinoxamine/methscopolamine/pseudoephedrine (KAR-bin-OX-a-meen/METH-skoe-POL-a-meen/SOO-doe-e-FED-rin)
Brand Name: Examples include Pannaz S and Pseudox M

Pannaz S syrup is used for:

Relieving congestion, sneezing, runny nose, and itchy, watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Pannaz S syrup is an antihistamine, decongestant, and anticholinergic combination. It works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also relieves nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and dries the chest by decreasing lung secretions.

Do NOT use Pannaz S syrup if:

  • you are allergic to any ingredient in Pannaz S syrup
  • you are pregnant or breast-feeding
  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
  • you have severe heart blood vessel disease; severe high blood pressure; narrow-angle glaucoma; severe bleeding; severe irritation of the esophagus or other serious problems with the esophagus (eg, esophageal achalasia); peptic ulcer; a blockage of your stomach, bowel, or bladder; bowel motility problems; severe bowel inflammation (eg, ulcerative colitis); certain muscle problems (eg, myasthenia gravis); or uncontrolled bleeding
  • you are unable to urinate or are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

Before using Pannaz S syrup:

Some medical conditions may interact with Pannaz S syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of diabetes, an enlarged prostate or other prostate problems, bladder or kidney problems, severe bowel problems, trouble urinating, high blood pressure, diarrhea, asthma, nerve problems, heart problems, blood vessel problems, blood clots, a hiatal hernia, an adrenal gland tumor, glaucoma, breathing problems during sleep, seizures, stroke, myasthenia gravis (muscle weakness), or an overactive thyroid

Some MEDICINES MAY INTERACT with Pannaz S syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alpha-blockers (eg, guanethidine, methyldopa, prazosin), beta-blockers (eg, atenolol), diuretics (eg, furosemide, hydrochlorothiazide), furazolidone, or MAOIs (eg, phenelzine) because the risk of high or low blood pressure may be increased
  • Alkalizers (eg, calcium or magnesium antacids), anticholinergics (eg, atropine, benztropine, dicyclomine), carbonic anhydrase inhibitors (eg, acetazolamide), ergotamine, sodium bicarbonate, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Pannaz S syrup's side effects
  • Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), certain stimulants (eg, doxapram, pseudoephedrine), cocaine, digoxin, droxidopa, potassium chloride, or sodium oxybate (GHB) because the risk of their side effects may be increased by Pannaz S syrup
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Pannaz S syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pannaz S syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pannaz S syrup:

Use Pannaz S syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Pannaz S syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Do not take Pannaz S syrup at the same time as an antacid, certain medicines for diarrhea (eg, attapulgite, bismuth, kaolin, pectin), or ketoconazole. Take these medicines 2 or 3 hours before or after you take Pannaz S syrup.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Pannaz S syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pannaz S syrup.

Important safety information:

  • Pannaz S syrup may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Pannaz S syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If your symptoms do not get better within 7 days or if they get worse or you develop a high fever or persistent headache, check with your doctor.
  • Pannaz S syrup may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Pannaz S syrup may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Pannaz S syrup may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Do not take diet or appetite control medicines while you are taking Pannaz S syrup without checking with your doctor.
  • Pannaz S syrup has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Pannaz S syrup may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Pannaz S syrup for a few days before the tests.
  • If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Pannaz S syrup.
  • Pannaz S syrup may interfere with certain lab tests. Be sure your doctor and lab personnel know that you are taking Pannaz S syrup.
  • Tell your doctor or dentist that you take Pannaz S syrup before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Pannaz S syrup may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Use Pannaz S syrup with caution in the ELDERLY; they may be more sensitive to its effects.
  • Caution is advised when using Pannaz S syrup in CHILDREN; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: It is not known if Pannaz S syrup can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pannaz S syrup while you are pregnant. Pannaz S syrup is found in breast milk. Do not breast-feed while taking Pannaz S syrup.

Possible side effects of Pannaz S syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing.

Proper storage of Pannaz S syrup:

Store Pannaz S syrup between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pannaz S syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about Pannaz S syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Pannaz S syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Pannaz S syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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