P-V Tussin

Generic Name: hydrocodone/pseudoephedrine (high-droe-KOE-dohn/soo-doe-e-FED-rin)
Brand Name: P-V Tussin

P-V Tussin is used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

P-V Tussin is a decongestant and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages. This allows you to breathe more easily. The cough suppressant works in the brain to decrease the cough reflex to help decrease a dry cough.

Do NOT use P-V Tussin if:

  • you are allergic to any ingredient in P-V Tussin or any other codeine or morphine related medicine (eg, codeine, oxycodone).
  • you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

Before using P-V Tussin:

Some medical conditions may interact with P-V Tussin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an abnormal heartbeat or other heart problems
  • if you have a history of adrenal gland problems (eg, tumor), high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, seizures or epilepsy, or an overactive thyroid
  • if you have or recently have had any head or brain injury, brain tumor, increased pressure in the brain, or infection of the brain or nervous system
  • if you have a history of any lung or breathing problems, asthma, stomach problems, bowel problems (eg, chronic inflammation or ulceration of the bowel), gallbladder problems (eg, gallstones), an enlarged prostate gland or other prostate problems, or you have had recent abdominal surgery
  • if you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with P-V Tussin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Naltrexone because it may decrease P-V Tussin's effectiveness
  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of P-V Tussin's side effects
  • Cimetidine and sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, and seizures may be increased
  • Digoxin and droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine because the risk of its side effects may be increased by P-V Tussin
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by P-V Tussin

This may not be a complete list of all interactions that may occur. Ask your health care provider if P-V Tussin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use P-V Tussin:

Use P-V Tussin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take P-V Tussin by mouth with or without food.
  • If you miss a dose of P-V Tussin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use P-V Tussin.

Important safety information:

  • P-V Tussin may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use P-V Tussin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take appetite suppressants while you are taking P-V Tussin without checking with your doctor.
  • P-V Tussin has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or take for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
  • P-V Tussin may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking P-V Tussin.
  • Tell your doctor or dentist that you take P-V Tussin before you receive any medical or dental care, emergency care, or surgery.
  • Use P-V Tussin with caution in the ELDERLY; they may be more sensitive to its effects.
  • P-V Tussin should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using P-V Tussin while you are pregnant. It is not known if P-V Tussin is found in breast milk. Do not breast-feed while taking P-V Tussin.

Possible side effects of P-V Tussin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness, excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of P-V Tussin:

Store P-V Tussin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep P-V Tussin out of the reach of children and away from pets.

General information:

  • If you have any questions about P-V Tussin, please talk with your doctor, pharmacist, or other health care provider.
  • P-V Tussin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about P-V Tussin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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