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Niacinamide with copper/ folic acid/ zinc

Generic Name: niacinamide with copper/folic acid/zinc (nye-a-SIN-a-mide/KOPP-er/FOE-lik AS-id/ZINK)
Brand Name: NIC 750

Niacinamide with copper/ folic acid/ zinc is used for:

Treating inflammatory skin conditions (eg, acne, rosacea) in patients with certain vitamin deficiencies (vitamin B3, zinc, copper, folic acid). It may also be used for other conditions as determined by your doctor.

Niacinamide with copper/folic acid/zinc is a multivitamin and mineral combination. It works by replacing vitamin B3, zinc, copper, and folic acid in the body, which can improve skin condition.

Do NOT use niacinamide with copper/ folic acid/ zinc if:

  • you are allergic to any ingredient in niacinamide with copper/folic acid/zinc
  • you have Wilson disease

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: View Frightful (But Dead Serious) Drug Side Effects

Before using niacinamide with copper/ folic acid/ zinc:

Some medical conditions may interact with niacinamide with copper/folic acid/zinc. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver problems, yellowing of the skin or eyes (jaundice), diabetes, anemia, or kidney problems
  • if you drink more than 3 alcohol-containing drinks per day

Some MEDICINES MAY INTERACT with niacinamide with copper/folic acid/zinc. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Fibrates (eg, gemfibrozil, fenofibrate) or HMG-CoA reductase inhibitors (statins) (eg, simvastatin) because side effects, such as muscle aches and weakness, may occur and may be a symptom of a serious medical condition called rhabdomyolysis
  • Hydantoins (eg, phenytoin) or penicillamine because their effectiveness may be decreased by niacinamide with copper/folic acid/zinc
  • Carbamazepine, fluorouracil, or primidone because the risk of their side effects may be increased by niacinamide with copper/folic acid/zinc

This may not be a complete list of all interactions that may occur. Ask your health care provider if niacinamide with copper/folic acid/zinc may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use niacinamide with copper/ folic acid/ zinc:

Use niacinamide with copper/folic acid/zinc as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take niacinamide with copper/folic acid/zinc by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • If you also take a quinolone antibiotic (eg, ciprofloxacin) or tetracycline antibiotic (eg, doxycycline), do not take it within 2 hours before or after taking niacinamide with copper/folic acid/zinc. Check with your doctor if you have questions.
  • If you miss a dose of niacinamide with copper/folic acid/zinc, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use niacinamide with copper/folic acid/zinc.

Important safety information:

  • Niacinamide with copper/folic acid/zinc may cause dizziness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use niacinamide with copper/folic acid/zinc with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not take large doses of vitamins while you use niacinamide with copper/folic acid/zinc unless your doctor tells you to.
  • Diabetes patients - Niacinamide with copper/folic acid/zinc may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Niacinamide with copper/folic acid/zinc should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use niacinamide with copper/folic acid/zinc if you are pregnant. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using niacinamide with copper/folic acid/zinc while you are pregnant. Niacinamide with copper/folic acid/zinc is found in breast milk. If you are or will be breast-feeding while you use niacinamide with copper/folic acid/zinc, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of niacinamide with copper/ folic acid/ zinc:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; dark urine; frequent hunger, thirst, or urination; persistent diarrhea, nausea, or vomiting; stomach pain; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of niacinamide with copper/folic acid/zinc:

Store niacinamide with copper/folic acid/zinc at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep niacinamide with copper/folic acid/zinc out of the reach of children and away from pets.

General information:

  • If you have any questions about niacinamide with copper/folic acid/zinc, please talk with your doctor, pharmacist, or other health care provider.
  • Niacinamide with copper/folic acid/zinc is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take niacinamide with copper/folic acid/zinc or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about niacinamide with copper/folic acid/zinc. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to niacinamide with copper/folic acid/zinc. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using niacinamide with copper/folic acid/zinc.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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