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Myochrysine

Generic Name: gold sodium thiomalate (golde SOE-dee-um THYE-oh-MAL-ate)
Brand Name: Myochrysine

Use of Myochrysine has a risk of toxic reactions ranging from severe to fatal. It is important to know the symptoms, which may include the following: blood in the urine, easy bruising or bleeding, itching, hives, rash, mouth sores, or persistent diarrhea. Be sure to discuss with your doctor what effects and symptoms to look for while taking Myochrysine. Lab tests will be required to monitor therapy.


Myochrysine is used for:

Treating rheumatoid arthritis as part of a complete program of therapy. It should not be used alone to treat arthritis. It may also be used for other conditions as determined by your doctor.

Myochrysine is an antirheumatic agent. It works by suppressing inflammation in the body.

Do NOT use Myochrysine if:

  • you are allergic to any ingredient in Myochrysine or have had a severe reaction to previous exposure to gold or other heavy metals

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Myochrysine:

Some medical conditions may interact with Myochrysine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes, congestive heart failure or other heart problems, circulation disorders, high blood pressure, Sjögren syndrome, liver or kidney problems, lupus, or recently had radiation therapy
  • if you have itching, dryness, peeling, or a skin rash (eg, eczema, hives)
  • if you have a history of blood disorders (eg, anemia) or you bleed easily

Some MEDICINES MAY INTERACT with Myochrysine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Penicillamine because the risk of kidney problems and blood disorders may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Myochrysine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Myochrysine:

Use Myochrysine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Myochrysine is usually administered as an injection at your doctor's office, hospital, or clinic. If you will be using Myochrysine at home, a health care provider will teach you how to use it. Be sure you understand how to use Myochrysine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Myochrysine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Myochrysine, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Myochrysine.

Important safety information:

  • After you receive an injection, you may experience flushing, dizziness, or sweating. These effects will usually disappear if you lie down for a few minutes.
  • Myochrysine may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Myochrysine. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Myochrysine may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have dark, tarry, or bloody stools.
  • Three to 6 months may pass before you feel the full effect of Myochrysine. Continue using injections during this time.
  • Joint pain may be worse for 1 or 2 days after your injection but it should end after the first few injections.
  • LAB TESTS, including complete blood cell counts and urine samples, may be performed while you use Myochrysine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Myochrysine while you are pregnant. Myochrysine is found in breast milk. Do not breast-feed while taking Myochrysine.

Possible side effects of Myochrysine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Stomach cramps.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blood in urine; cough; dark urine; decreased urination; fainting; fast or slow heartbeat; fever, chills, or sore throat; flushing of the skin; metallic taste; mouth sores; nausea; pain or numbness in the hands or feet; persistent diarrhea; purple blotches or other skin spots; redness or peeling of the skin; seizures; severe or persistent stomach pain; shortness of breath; thickening of the tongue; unusual bleeding or bruising; unusual tiredness or weakness; vision problems; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Myochrysine:

Myochrysine is usually handled and stored by a health care provider. If you are using Myochrysine at home, store Myochrysine as directed by your pharmacist or health care provider. Keep Myochrysine out of the reach of children and away from pets.

General information:

  • If you have any questions about Myochrysine, please talk with your doctor, pharmacist, or other health care provider.
  • Myochrysine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Myochrysine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Myochrysine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Myochrysine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Myochrysine.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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