Methscopolamine

Generic Name: methscopolamine (meth-skoe-POL-uh-meen)
Brand Name: Pamine and Pamine Forte

Methscopolamine is used for:

Treating peptic ulcers in combination with other medicines. It also may be used for other conditions as determined by your doctor.

Methscopolamine is an anticholinergic. It works by decreasing stomach acid production and by relaxing the muscles in the stomach and intestines.

Do NOT use methscopolamine if:

  • you are allergic to any ingredient in methscopolamine
  • you have glaucoma, blockage of the bladder, certain problems with your esophagus (eg, decreased esophageal motility, severe irritation caused by reflux), certain stomach or intestinal problems (eg, blockage, lack of muscle tone, or ulcerative colitis), heart problems caused by blood loss, or muscle problems (eg, myasthenia gravis)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using methscopolamine:

Some medical conditions may interact with methscopolamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have nerve problems, severe bowel problems, prostate problems, heart problems, heart failure, a hernia, a predisposition of glaucoma or open-angle glaucoma, or urinary retention

Some MEDICINES MAY INTERACT with methscopolamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticholinergic medicines (eg, benztropine, hyoscyamine, or trihexyphenidyl), certain medicines for mental or mood disorders (eg, thioridazine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of methscopolamine's side effects
  • Beta-blockers (eg, propanolol) or digoxin because the risk of their side effects may be increased by methscopolamine

This may not be a complete list of all interactions that may occur. Ask your health care provider if methscopolamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use methscopolamine:

Use methscopolamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take methscopolamine by mouth 30 minutes before meals and at bedtime, or as directed by your health care provider.
  • Do not take an antacid within 1 hour before or 2 hours after you take methscopolamine.
  • If you miss a dose of methscopolamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use methscopolamine.

Important safety information:

  • Methscopolamine may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use methscopolamine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Methscopolamine may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Methscopolamine may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using methscopolamine without checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Antacids may decrease the effectiveness of methscopolamine. Talk to your doctor before taking any antacids while taking methscopolamine.
  • Use methscopolamine with caution in the ELDERLY; they may be more sensitive to its effects, especially if they have weak intestines or constipation.
  • Methscopolamine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using methscopolamine while you are pregnant. It is not known if methscopolamine is found in breast milk. Do not breast-feed while taking methscopolamine.

Possible side effects of methscopolamine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloated feeling; blurred vision; constipation; decreased sweating; difficulty sleeping; dilation of pupils; dizziness; drowsiness; dry mouth; headache; loss of taste; nausea; nervousness; urinary hesitancy or retention.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in heartbeat; diarrhea; difficulty focusing your eyes; difficulty urinating; pounding in the chest; rapid heart rate; unusual weakness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include abnormal behavior; blurred vision; circulatory problems; coma; difficulty breathing; dilated pupils; disorientation; excessive thirst; excitement; flushing; low blood pressure; muscle weakness; nausea; paralysis; restlessness; seizures; unusual dizziness or drowsiness; unusually dry mouth; vomiting.

Proper storage of methscopolamine:

Store methscopolamine between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep methscopolamine out of the reach of children and away from pets.

General information:

  • If you have any questions about methscopolamine, please talk with your doctor, pharmacist, or other health care provider.
  • Methscopolamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take methscopolamine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about methscopolamine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to methscopolamine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using methscopolamine.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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