Methadone dispersible tablets

Pronunciation

Generic Name: methadone (METH-uh-dohn)
Brand Name: Methadose

Fatal overdose of methadone dispersible tablets is possible if you take more than the recommended dose. Overdose is also possible if you also consume alcohol or other medications that affect your mind or behavior. Because of the risks associated with methadone dispersible tablets, you should only receive it from approved treatment programs. Obtaining it any other way is illegal.


Methadone dispersible tablets is used for:

Temporarily treating a narcotic addiction as part of a treatment program. It may also be used for other conditions as determined by your doctor.

Methadone dispersible tablets is a synthetic narcotic analgesic with multiple actions similar to those of morphine, including pain relief. It also provides sedation and temporary maintenance treatment of narcotic addiction.

Do NOT use methadone dispersible tablets if:

  • you are allergic to any ingredient in methadone dispersible tablets
  • you have diarrhea due to poisoning, pseudomembranous colitis, or hypercapnia (abnormally increased carbon dioxide tension in your arteries), or are taking sodium oxybate (GHB)
  • you drink alcohol

Contact your doctor or health care provider right away if any of these apply to you.

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Before using methadone dispersible tablets:

Some medical conditions may interact with methadone dispersible tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma, prostate problems, a brain tumor, heart problems, liver disease, breathing problems, seizures, bowel problems, urination problems, a lesion or increased pressure on the brain, low blood levels of potassium or magnesium, underactive thyroid, anxiety, low blood volume, kidney problems, Addison disease, or suicidal thoughts
  • if you have ever abused drugs, have head trauma, or have had GI tract surgery

Some MEDICINES MAY INTERACT with methadone dispersible tablets. Tell your health care provider if you are taking any other medicines, especially any of the following.

  • Efavirenz, HIV protease inhibitors (eg, ritonavir), naltrexone, narcotic antagonists (eg, naloxone), nevirapine, pentazocine, risperidone, or St. John's wort because they may decrease methadone dispersible tablets's effectiveness
  • Barbiturate anesthetics (eg, thiopental), cimetidine, ethanol, fluconazole, fluvoxamine, ketorolac, quinolones (eg, ciprofloxacin), or sodium oxybate (GHB) because side effects such as sedation, confusion and slowed breathing may occur
  • Barbiturate anesthetics (eg, thiopental), desipramine, sodium oxybate (GHB), or zidovudine because their actions and the risk of their side effects may be increased by methadone dispersible tablets
  • Mexiletine or nucleoside reverse transcriptase inhibitors (eg, lamivudine) because their effectiveness may be decreased by methadone dispersible tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if methadone dispersible tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use methadone dispersible tablets:

Use methadone dispersible tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take methadone dispersible tablets by mouth with or without food.
  • Methadone dispersible tablets must be administered under close medical supervision.
  • Take methadone dispersible tablets on a regular schedule to get the most benefit from it. It is more effective in preventing pain than in treating pain after it occurs.
  • Methadone dispersible tablets is for oral use only and must not be injected.
  • If you miss a dose of methadone dispersible tablets and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use methadone dispersible tablets.

Important safety information:

  • Methadone dispersible tablets may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use methadone dispersible tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using methadone dispersible tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Methadone dispersible tablets may cause constipation. Constipation may be avoided by using a stool softener or fiber laxative.
  • Tell your doctor or dentist that you take methadone dispersible tablets before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including liver function, kidney function, and complete blood count, may be performed while you use methadone dispersible tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use methadone dispersible tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Methadone dispersible tablets should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using methadone dispersible tablets while you are pregnant. Methadone dispersible tablets is found in breast milk. If you are or will be breast-feeding while you use methadone dispersible tablets, check with your doctor. Discuss any possible risks to your baby.

Some people who use methadone dispersible tablets for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking methadone dispersible tablets suddenly, you may have WITHDRAWAL symptoms. These may include convulsions, tremor, stomach and muscle cramps, vomiting, and sweating. Do not stop therapy suddenly or change the dosage without asking your doctor. Discuss overuse with your doctor or pharmacist.

Possible side effects of methadone dispersible tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; headache; lightheadedness; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive drowsiness; fainting; itching; pounding in the chest; seizures; shortness of breath; slow heartbeat; sweating.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; deep sleep; difficult or slow breathing, especially when lying down; dizziness; drowsiness; lightheadedness; loss of consciousness; low body temperature; pinpoint pupils; shock; shortness of breath; slow heartbeat.

Proper storage of methadone dispersible tablets:

Store methadone dispersible tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep methadone dispersible tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about methadone dispersible tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Methadone dispersible tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about methadone dispersible tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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