Generic Name: mecamylamine (mek-ah-MIL-a-meen)
Brand Name: Inversine
Mecamylamine is used for:
Treating severe high blood pressure. It may also be used for other conditions as determined by your doctor.
Mecamylamine is an antihypertensive agent. It works by relaxing and dilating (widening) blood vessels. Blood flows more freely and at a lower pressure through dilated blood vessels, which helps to lower blood pressure.
Do NOT use mecamylamine if:
- you are allergic to any ingredient in mecamylamine
- you have heart problems or have recently had a heart attack
- you are taking an antibiotic or sulfonamide (eg, sulfamethoxazole)
- you have glaucoma, certain complications from kidney disease (eg, increased levels of waste products in the blood), or narrowing of the passage from the stomach into the intestine (pyloric stenosis)
Contact your doctor or health care provider right away if any of these apply to you.
Before using mecamylamine:
Some medical conditions may interact with mecamylamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have recently suffered a stroke or you have hardening of the arteries or difficulty urinating due to an enlarged prostate ornarrow bladder neck
Some MEDICINES MAY INTERACT with mecamylamine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Urinary alkalinizers because the blood-pressure lowering effects of this drug may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if mecamylamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use mecamylamine:
Use mecamylamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take mecamylamine with food.
- Mecamylamine comes with an additional patient leaflet. Read it carefully and reread it each time you get mecamylamine refilled.
- Take mecamylamine on a regular schedule around the clock, unless otherwise directed by your doctor.
- If you miss a dose of mecamylamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use mecamylamine.
Important safety information:
- Mecamylamine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to mecamylamine. Using mecamylamine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Mecamylamine may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
- Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel "normal." Contact your doctor or pharmacist about any new symptoms.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using mecamylamine.
- Stop taking mecamylamine and contact your health care provider at once if frequent loose bowel movements with stomach bloating and decreased gas occur.
- Mecamylamine is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using mecamylamine during pregnancy. It is unknown if mecamylamine is excreted in breast milk. Do not breast-feed while you are taking mecamylamine.
Possible side effects of mecamylamine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; constipation (sometimes preceded by small, frequent liquid stools); decreased sex drive; dizziness; dry mouth; enlarged pupils; impotence;inflammation of the tongue; lightheadedness; loss of appetite; nausea; urinary retention; vomiting.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal movements; abnormal thinking; difficulty urinating; fainting; frequent loose bowel movements with stomach bloating and decreased gas; seizure; tremors.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; fainting; irregular heartbeat.Proper storage of mecamylamine:
Store mecamylamine at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep mecamylamine out of the reach of children and away from pets.
- If you have any questions about mecamylamine, please talk with your doctor, pharmacist, or other health care provider.
- Mecamylamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about mecamylamine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.