Generic Name: loteprednol/tobramycin (LOE-te-PRED-nol/TOE-bra-MYE-sin)
Brand Name: Zylet
Loteprednol/tobramycin drops is used for:
Treating certain types of eye inflammation in which an infection or risk of infection is present.
Loteprednol/tobramycin drops is a combination of a corticosteroid and antibiotic. It reduces inflammation and treats or protects against infection due to certain bacteria.
Do NOT use loteprednol/tobramycin drops if:
- you are allergic to any ingredient in loteprednol/tobramycin drops or to similar medicines, including corticosteroids or aminoglycoside antibiotics.
- you have a viral disease in the eye, including herpes simplex keratitis (dendritic keratitis), vaccinia, or varicella
- you have a mycobacterial or fungal infection of the eye
Contact your doctor or health care provider right away if any of these apply to you.
Before using loteprednol/tobramycin drops:
Some medical conditions may interact with loteprednol/tobramycin drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have glaucoma, thinning of certain parts of the eye (the cornea or the sclera), or a history of herpes simplex infection, or have recently had cataract surgery
- if you have diabetes or wear contact lenses
Some MEDICINES MAY INTERACT with loteprednol/tobramycin drops. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Certain diuretic medicines (eg, furosemide), cyclosporine, nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen), or other medicines containing aminoglycoside antibiotics (eg, tobramycin, gentamicin) because the risk of their side effects may be increased by loteprednol/tobramycin drops
This may not be a complete list of all interactions that may occur. Ask your health care provider if loteprednol/tobramycin drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use loteprednol/tobramycin drops:
Use loteprednol/tobramycin drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Loteprednol/tobramycin drops is to be used as eye drops. It is not to be injected into the eye.
- Shake well before each use.
- To use loteprednol/tobramycin drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- To clear up your infection completely, use loteprednol/tobramycin drops for the full course of treatment. Keep using it even if you feel better in a few days.
- Loteprednol/tobramycin drops is usually used for a maximum of 2 weeks. If it is used for longer than 10 days, eye exams may be required.
- If you miss a dose of loteprednol/tobramycin drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use loteprednol/tobramycin drops.
Important safety information:
- Loteprednol/tobramycin drops may cause blurred vision. Use loteprednol/tobramycin drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
- If your symptoms do not get better after 2 days or if they get worse, contact your health care provider.
- Soft contact lenses may absorb a chemical in loteprednol/tobramycin drops. Do not wear contact lenses while you are using loteprednol/tobramycin drops.
- Tell your doctor or dentist that you take loteprednol/tobramycin drops before you receive any medical or dental care, emergency care, or surgery.
- Loteprednol/tobramycin drops only works against bacteria; it does not treat viral infections (eg, the common cold).
- Be sure to use loteprednol/tobramycin drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of loteprednol/tobramycin drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Lab tests, including eye exams, may be performed while you use loteprednol/tobramycin drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using loteprednol/tobramycin drops while you are pregnant. It is not known if loteprednol/tobramycin drops is found in breast milk. If you are or will be breast-feeding while you use loteprednol/tobramycin drops, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of loteprednol/tobramycin drops:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Burning or stinging upon using loteprednol/tobramycin drops; mild itching, discomfort, or redness of the eye.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; sensitivity to light; severe or worsening pain or inflammation, redness, swelling, or discharge from the eye or eyelid; unusual tearing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of loteprednol/tobramycin drops:
Store upright, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep loteprednol/tobramycin drops out of the reach of children and away from pets.
- If you have any questions about loteprednol/tobramycin drops, please talk with your doctor, pharmacist, or other health care provider.
- Loteprednol/tobramycin drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take loteprednol/tobramycin drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about loteprednol/tobramycin drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to loteprednol/tobramycin drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using loteprednol/tobramycin drops.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.