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Lo-Hist 12 12-hour sustained-release tablets

Generic Name: brompheniramine (brome-fen-EER-a-meen)
Brand Name: Examples include Lodrane 12 Hour and Lo-Hist 12

Lo-Hist 12 12-hour sustained-release tablets is used for:

Treating and preventing symptoms of hay fever, other allergies, and colds. It may also be used for other conditions as determined by your doctor.

Lo-Hist 12 12-hour sustained-release tablets is an antihistamine. It works by blocking the action of histamine, a chemical released during allergic reactions.

Do NOT use Lo-Hist 12 12-hour sustained-release tablets if:

  • you are allergic to any ingredient in Lo-Hist 12 12-hour sustained-release tablets
  • you are breast-feeding
  • you have narrow-angle glaucoma, or a peptic or stomach ulcer
  • you are unable to urinate or you are having an asthma attack
  • you are taking sodium oxybate (GHB) or you have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) in the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Top Prevention Tips: Springtime Allergies

Before using Lo-Hist 12 12-hour sustained-release tablets:

Some medical conditions may interact with Lo-Hist 12 12-hour sustained-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an enlarged prostate, difficulty urinating or severe constipation
  • if you have an overactive thyroid, asthma, increased pressure in the eyes, glaucoma, heart disease, or high blood pressure

Some MEDICINES MAY INTERACT with Lo-Hist 12 12-hour sustained-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because the risk of severe drowsiness may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lo-Hist 12 12-hour sustained-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lo-Hist 12 12-hour sustained-release tablets:

Use Lo-Hist 12 12-hour sustained-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Lo-Hist 12 12-hour sustained-release tablets may be taken with food if it upsets your stomach.
  • Swallow whole. Do not break, crush, or chew before swallowing.
  • If you miss a dose of Lo-Hist 12 12-hour sustained-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lo-Hist 12 12-hour sustained-release tablets.

Important safety information:

  • Lo-Hist 12 12-hour sustained-release tablets may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Lo-Hist 12 12-hour sustained-release tablets. Using Lo-Hist 12 12-hour sustained-release tablets alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medicines that cause drowsiness (eg, sedatives, tranquilizers) while taking Lo-Hist 12 12-hour sustained-release tablets. Lo-Hist 12 12-hour sustained-release tablets will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Risk of side effects may be increased with high doses or prolonged use. Do NOT exceed the recommended dose or take Lo-Hist 12 12-hour sustained-release tablets for longer than prescribed without checking with your doctor.
  • Use Lo-Hist 12 12-hour sustained-release tablets with caution in the ELDERLY because they may be more sensitive to its effects, especially dizziness, drowsiness, dry mouth, and trouble urinating.
  • Use Lo-Hist 12 12-hour sustained-release tablets with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • Lo-Hist 12 12-hour sustained-release tablets may interfere with results of some lab tests, including allergy skin tests. Inform lab attendants that you are taking Lo-Hist 12 12-hour sustained-release tablets.
  • PREGNANCY and BREAST-FEEDING: It is unknown if Lo-Hist 12 12-hour sustained-release tablets can cause harm to the fetus. If you become pregnant while taking Lo-Hist 12 12-hour sustained-release tablets, discuss with your doctor the benefits and risks of using Lo-Hist 12 12-hour sustained-release tablets during pregnancy. It is unknown if Lo-Hist 12 12-hour sustained-release tablets is excreted in breast milk. Do not breast-feed while taking Lo-Hist 12 12-hour sustained-release tablets.

Possible side effects of Lo-Hist 12 12-hour sustained-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat; fever; mental or mood changes; shortness of breath; sore throat; unusual bleeding or bruising; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bizarre behavior; constipation; enlarged pupils; excitement; flushing; hallucinations; seizures; severe dizziness; severe drowsiness.

Proper storage of Lo-Hist 12 12-hour sustained-release tablets:

Store Lo-Hist 12 12-hour sustained-release tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep Lo-Hist 12 12-hour sustained-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Lo-Hist 12 12-hour sustained-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Lo-Hist 12 12-hour sustained-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Lo-Hist 12 12-hour sustained-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Lo-Hist 12 12-hour sustained-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lo-Hist 12 12-hour sustained-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Lo-Hist 12 12-hour sustained-release tablets.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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