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Lidocaine/ tetracaine patch

Generic Name: lidocaine/tetracaine (LYE-doe-kane/TET-ra-kane)
Brand Name: Synera

Lidocaine/ tetracaine patch is used for:

Numbing the skin before certain medical procedures. It may also be used for other conditions as determined by your doctor.

Lidocaine/tetracaine patch is a local anesthetic. It works by blocking nerves from sending pain signals to the brain.

Do NOT use lidocaine/ tetracaine patch if:

  • you are allergic to any ingredient in lidocaine/tetracaine patch, other local anesthetics, or para-aminobenzoic acid (PABA)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using lidocaine/ tetracaine patch:

Some medical conditions may interact with lidocaine/tetracaine patch. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substance
  • if you have a history of methemoglobinemia or glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • if you have liver problems or pseudocholinesterase deficiency
  • if you have been very ill or have very poor health

Some MEDICINES MAY INTERACT with lidocaine/tetracaine patch. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antiarrhythmics (eg, amiodarone, dofetilide, mexiletine, tocainide), other local anesthetics (eg, benzocaine), or other medicines containing lidocaine or tetracaine because the risk of side effects or toxic effects, including heart or nerve problems, may be increased
  • Acetaminophen, acetanilide, aniline dyes (eg, p-phenylenediamine), benzocaine, chloroquine, dapsone, naphthalene, nitrates (eg, nitroglycerin, nitroprusside), nitrites (eg, sodium nitrite), nitrofurantoin, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine, or sulfonamides (eg, sulfamethoxazole) because the risk of methemoglobinemia may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if lidocaine/tetracaine patch may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use lidocaine/ tetracaine patch:

Use lidocaine/tetracaine patch as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Lidocaine/tetracaine patch is usually applied at your doctor's office, hospital, or clinic. It is usually applied for 20 to 30 minutes before certain medical procedures.
  • Apply the patch right away after opening the pouch.
  • Do not cut or tear the patch, remove the top cover, or damage the patch in any way. This could cause the patch to overheat and damage the skin.
  • Do not get water on the patch. Keep the patch dry.
  • Do not cover the holes on the top side of the patch. This may prevent the patch from working properly.
  • Lidocaine/tetracaine patch should only be used on normal, unbroken skin. Do not apply to damaged or inflamed skin.
  • Apply the patch as directed. Press firmly around the edges of the patch to be sure it sticks.
  • Wash your hands right away after using lidocaine/tetracaine patch.
  • After removing the used patch, fold it in half with the sticky sides together. Discard the patch out of the reach of children and away from pets.
  • If you miss a dose of lidocaine/tetracaine patch, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use lidocaine/tetracaine patch.

Important safety information:

  • Lidocaine/tetracaine patch is for external use only. Avoid contact with your eyes, nose, or mouth. If contact with any of these areas occurs, rinse with plenty of water or saline. Protect the eye until feeling returns.
  • Lidocaine/tetracaine patch blocks pain and feeling in the skin. Be careful not to injure the treated skin by scratching, rubbing, or coming into contact with extreme cold or heat.
  • Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Check with your doctor before you receive any vaccines while you are using lidocaine/tetracaine patch.
  • Tell your doctor or dentist that you use lidocaine/tetracaine patch before you receive any medical or dental care, emergency care, or surgery.
  • If you will be having a magnetic resonance imaging (MRI) scan, be sure your doctor and lab personnel know you are using lidocaine/tetracaine patch. You will need to remove this patch before an MRI.
  • Lidocaine/tetracaine patch may cause harm if swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • If the patient is a young child, be sure to watch the child closely to prevent the accidental swallowing of lidocaine/tetracaine patch.
  • Use lidocaine/tetracaine patch with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using lidocaine/tetracaine patch while you are pregnant. Lidocaine/tetracaine patch is found in breast milk. If you are or will be breast-feeding while you use lidocaine/tetracaine patch, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of lidocaine/ tetracaine patch:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations; pale skin, redness, or swelling at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; hoarseness); burning, irritation, or severe redness or swelling at the application site; confusion; feeling of being unusually warm or cold; feeling very nervous and excitable; mental or mood changes; nausea; ringing in the ears; slow or shallow breathing; symptoms of methemoglobinemia (eg, bluish-grey color of the lips, nails, or skin; fainting; fast, slow, or irregular heartbeat; seizures; severe dizziness, drowsiness, headache, sluggishness, or tiredness; shortness of breath); tremors or twitching; vision changes; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of lidocaine/tetracaine patch:

Store lidocaine/tetracaine patch at room temperature, 77 degrees F (25 degrees C), in a tightly closed container. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep lidocaine/tetracaine patch out of the reach of children and away from pets.

General information:

  • If you have any questions about lidocaine/tetracaine patch, please talk with your doctor, pharmacist, or other health care provider.
  • Lidocaine/tetracaine patch is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take lidocaine/tetracaine patch or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about lidocaine/tetracaine patch. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to lidocaine/tetracaine patch. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using lidocaine/tetracaine patch.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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