Lidocaine/ hydrocortisone cream

Generic Name: lidocaine/hydrocortisone (LYE-doe-kane/HYE-droe-KOR-ti-sone/SIL-ee-um)
Brand Name: Xyralid RC

Lidocaine/ hydrocortisone cream is used for:

Treating pain, itching, soreness, and discomfort caused by hemorrhoids or other anal conditions. It also helps to relieve constipation.

Lidocaine/hydrocortisone cream is a kit that contains an anesthetic and corticosteroid cream and a bulk-forming laxative. The anesthetic works by helping to decrease soreness and discomfort. The corticosteroid works by reducing swelling, redness, and itching. The bulk-forming laxative works by absorbing water in the intestines. This helps to soften and stool so it can be more easily passed.

Do NOT use lidocaine/ hydrocortisone cream if:

  • you are allergic to any ingredient in lidocaine/hydrocortisone cream or to similar medications (eg, dibucaine)
  • you have a tuberculous or fungal skin infection, a herpes simplex skin infection, chickenpox, shingles, or a skin infection following smallpox vaccination

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Hemorrhoids: A Common Ailment with Frequent Questions

Image Credit: U.S. FDA/Drugs.com

Before using lidocaine/ hydrocortisone cream:

Some medical conditions may interact with lidocaine/hydrocortisone cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any anesthetic medicine
  • if you have a history of thinning skin, skin infection, or other skin disorders
  • if you have recently received a vaccination or if you have ever had a positive tuberculin (TB) skin test
  • if you have stomach pain, nausea, vomiting, rectal bleeding, or trouble swallowing
  • if you have liver problems, diabetes, high blood sugar levels, very poor health, stomach or bowel pain, nausea, or vomiting; or if you have had a sudden change in bowel habits persisting for more than 2 weeks

Some MEDICINES MAY INTERACT with lidocaine/hydrocortisone cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Class IA antiarrhythmics (eg, disopyramide) because the risk of their side effects may be increased by lidocaine/hydrocortisone cream

This may not be a complete list of all interactions that may occur. Ask your health care provider if lidocaine/hydrocortisone cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use lidocaine/ hydrocortisone cream:

Use lidocaine/hydrocortisone cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • To use the rectal cream: Clean the affected area with the cleansing wipe as directed before you apply the cream. Attach the applicator to the tube of rectal cream and squeeze gently until a small amount of cream shows. Lubricate the tip of the applicator with the cream and apply as directed by your doctor.
  • To use the bulk-forming laxative: Mix the contents of the packet with fluid in the shaker cup provided. Take the laxative with plenty of fluid according to the directions provided or as directed by your doctor.
  • If you miss a dose of lidocaine/hydrocortisone cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use lidocaine/hydrocortisone cream.

Important safety information:

  • Do not get lidocaine/hydrocortisone cream in your eyes, ears, nose, or mouth. If you get it in any of these areas, rinse at once with cool tap water.
  • If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
  • Do NOT use more than the recommended dose, use more often, or use for longer than prescribed without checking with your doctor.
  • If you use topical products too often, your condition may become worse.
  • Lidocaine/hydrocortisone cream may cause a numbing effect at the application site. Do not scratch, rub, or expose the area to extreme hot or cold temperature until the numbness is gone.
  • Lidocaine/hydrocortisone cream has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do not take additional laxatives or stool softeners with lidocaine/hydrocortisone cream unless directed by your doctor.
  • Tell your doctor if you fail to have a bowel movement even after using lidocaine/hydrocortisone cream.
  • Taking the bulk-forming laxative without enough liquid may cause it to swell and block your throat or esophagus and may cause choking. If you experience chest pain, vomiting, or difficulty swallowing or breathing after taking the laxative, seek immediate medical attention.
  • Tell your doctor or dentist that you take lidocaine/hydrocortisone cream before you receive any medical or dental care, emergency care, or surgery.
  • Use lidocaine/hydrocortisone cream with caution in the ELDERLY; they may be more sensitive to its effects.
  • Lidocaine/hydrocortisone cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if lidocaine/hydrocortisone cream can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using lidocaine/hydrocortisone cream while you are pregnant. It is not known if lidocaine/hydrocortisone cream is found in breast milk after topical use. If you are or will be breast-feeding while you use lidocaine/hydrocortisone cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of lidocaine/ hydrocortisone cream:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal fullness; mild stinging, burning, redness, or discoloration at the application site; minor bloating.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty swallowing; excessive irritation; rectal bleeding; skin infection (eg, redness, swelling, pus discharge); vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Lidocaine/hydrocortisone cream may be harmful if swallowed.

Proper storage of lidocaine/hydrocortisone cream:

Store lidocaine/hydrocortisone cream at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat and light. Do not store in the bathroom. Protect from freezing. Keep lidocaine/hydrocortisone cream out of the reach of children and away from pets.

General information:

  • If you have any questions about lidocaine/hydrocortisone cream, please talk with your doctor, pharmacist, or other health care provider.
  • Lidocaine/hydrocortisone cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about lidocaine/hydrocortisone cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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