Generic Name: diphtheria, tetanus toxoids, acellular pertussis, and inactivated poliovirus vaccine (dif-THEER-ee-a/TET-a-nus/aye-SELL-yoo-ler pur-TUS-is/POE-lee-oh-VYE-rus)
Brand Name: Examples include Kinrix and Quadracel
Kinrix is used for:
Immunizing children 4 to 6 years old against diphtheria, tetanus, pertussis (whooping cough), and polio. Kinrix is used as the fourth or fifth dose in this vaccine schedule.
Kinrix is a vaccine. It works by providing long-term protection against diphtheria, tetanus, pertussis, and polio by stimulating the body to produce antibodies against bacteria or their toxins that cause these conditions.
Do NOT use Kinrix if:
- you are allergic to any ingredient in Kinrix, including neomycin or polymyxin B
- you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) or neurologic reaction to any previous dose of this or a similar vaccine
- you had a decreased level of consciousness, had prolonged seizures, or have been in a coma within 7 days of receiving any pertussis-containing vaccine
- you have a progressive neurologic disorder, including infantile spasms, uncontrolled epilepsy (seizures), or decreasing level of consciousness or coma
Contact your doctor or health care provider right away if any of these apply to you.
Before using Kinrix:
Some medical conditions may interact with Kinrix. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances, especially latex
- if you have a fever, infection, illness, brain disease (eg, encephalopathy), diarrhea, or a history of seizures, or if you are dehydrated
- if you have a weak immune system, or if you are receiving radiation therapy or chemotherapy
- if you have a history of Guillain-BarrÃ© syndrome after receiving a previous tetanus vaccine
- if you have received a previous pertussis vaccine and experienced any of the following symptoms afterwards: severe fever, fainting, unresponsiveness, persistent crying for more than 3 hours, or seizures with or without fever
Some MEDICINES MAY INTERACT with Kinrix. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Immunosuppressive therapy including corticosteroids (eg, prednisone), antimetabolites (eg, methotrexate), alkylating agents (eg, cyclophosphamide), or cytotoxic drugs (eg, dactinomycin) because they may decrease Kinrix's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Kinrix may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Kinrix:
Use Kinrix as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Kinrix is given as an injection at your doctor's office, hospital, or a clinic. Contact your health care provider if you have any questions.
- If you miss a dose of the vaccine series, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use Kinrix.
Important safety information:
- If you have a fever or infection, the doctor may delay giving the vaccine. Discuss the risks and benefits of vaccination with the doctor.
- There are various combinations of vaccines available. Based on previous reactions to vaccines, the doctor will determine the most appropriate ones to use.
- Keep all doctor and lab appointments while using Kinrix.
- Kinrix may not protect everyone who receives it. Talk with your doctor.
- This vaccine is not approved for persons older than 6 years old or in CHILDREN younger than 4 years old. Talk with the doctor.
- PREGNANCY and BREAST-FEEDING: Kinrix is not recommended for use in persons older than 6 years old.
Possible side effects of Kinrix:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Bruising, irritation, redness, pain, swelling, or tenderness at the injection site (these may last a few days); drowsiness; headache; loss of appetite; mild fever; muscle pain; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, numbness, or tingling; collapse or unresponsiveness; confusion; fainting; fussiness, irritability, or excessive crying; high fever; one-sided weakness; seizures; severe or persistent drowsiness; severe stomach pain; slurred speech; swelling of the arm or lymph nodes; unusual bruising or bleeding; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Kinrix:
Kinrix is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.
- If you have any questions about Kinrix, please talk with your doctor, pharmacist, or other health care provider.
- Kinrix is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Kinrix or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Kinrix. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Kinrix. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Kinrix.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.