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Isosorbide mononitrate sustained-release tablets

Pronunciation

Generic Name: isosorbide mononitrate (EYE-soe-SOR-bide MON-oh-NYE-trate)
Brand Name: Imdur

Isosorbide mononitrate sustained-release tablets is used for:

Preventing angina (chest pain) caused by heart disease.

Isosorbide mononitrate sustained-release tablets is a nitrate vasodilator. It works by widening the blood vessels in the body. This reduces the workload of the heart and helps to relieve chest pain.

Do NOT use isosorbide mononitrate sustained-release tablets if:

  • you are allergic to any ingredient in isosorbide mononitrate sustained-release tablets or to other nitrate medicines
  • you are also taking a phosphodiesterase type 5 inhibitor (eg, sildenafil, tadalafil, vardenafil)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using isosorbide mononitrate sustained-release tablets:

Some medical conditions may interact with isosorbide mononitrate sustained-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, heart failure, heart attack, hypertrophic cardiomyopathy), low blood pressure, blood problems (eg, anemia), dehydration, bleeding in the brain, an overactive thyroid, or have had a recent head injury

Some MEDICINES MAY INTERACT with isosorbide mononitrate sustained-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Calcium channel blockers (eg, diltiazem, verapamil) or phosphodiesterase type 5 inhibitors (eg, sildenafil, tadalafil, vardenafil) because the risk of severe low blood pressure may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if isosorbide mononitrate sustained-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use isosorbide mononitrate sustained-release tablets:

Use isosorbide mononitrate sustained-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take isosorbide mononitrate sustained-release tablets by mouth with or without food.
  • Swallow isosorbide mononitrate sustained-release tablets whole. Do not break, crush, or chew before swallowing. Some strengths of isosorbide mononitrate sustained-release tablets may be broken in half. If you have difficulty swallowing the tablet whole, ask your pharmacist if your strength of medicine may be broken in half.
  • Take isosorbide mononitrate sustained-release tablets with one-half glass of water or other liquid.
  • Do not suddenly stop taking isosorbide mononitrate sustained-release tablets. You may have an increased risk of side effects (eg, an angina attack). If you need to stop isosorbide mononitrate sustained-release tablets or add a new medicine, your doctor will gradually lower your dose.
  • If you miss a dose of isosorbide mononitrate sustained-release tablets, take it as soon as possible. If it is late in the day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use isosorbide mononitrate sustained-release tablets.

Important safety information:

  • Isosorbide mononitrate sustained-release tablets may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use isosorbide mononitrate sustained-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Isosorbide mononitrate sustained-release tablets may cause dizziness or lightheadedness; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do not drink alcohol while you are taking isosorbide mononitrate sustained-release tablets.
  • When you begin taking isosorbide mononitrate sustained-release tablets, headaches are likely to occur. Ask your doctor for instructions on ways to reduce this side effect.
  • Isosorbide mononitrate sustained-release tablets should not be used to stop an attack of angina; it is intended only for prevention of an attack.
  • Isosorbide mononitrate sustained-release tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking isosorbide mononitrate sustained-release tablets.
  • Isosorbide mononitrate sustained-release tablets should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using isosorbide mononitrate sustained-release tablets while you are pregnant. It is not known if isosorbide mononitrate sustained-release tablets is found in breast milk. If you are or will be breast-feeding while you use isosorbide mononitrate sustained-release tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of isosorbide mononitrate sustained-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; fainting; numbness of an arm or leg; severe stomach pain; sharp or crushing chest pain; sudden leg pain; sudden, severe headache; sudden shortness of breath; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include breathing problems; confusion; dizziness; fainting; fever; flushing; headache; increased pressure in the head; irregular heartbeat; loss of appetite; nausea; paralysis; sweating; visual disturbances; vomiting.

Proper storage of isosorbide mononitrate sustained-release tablets:

Store isosorbide mononitrate sustained-release tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep isosorbide mononitrate sustained-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about isosorbide mononitrate sustained-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Isosorbide mononitrate sustained-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take isosorbide mononitrate sustained-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about isosorbide mononitrate sustained-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to isosorbide mononitrate sustained-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using isosorbide mononitrate sustained-release tablets.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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