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Insulin regular innolets

Pronunciation

Generic Name: insulin regular (IN-su-lin)
Brand Name: Examples include Humulin R and Novolin R

Insulin regular innolets is used for:

Treating diabetes mellitus.

Insulin regular innolets is a fast-acting form of the hormone insulin. It works by helping your body to use sugar properly. This lowers the amount of glucose in the blood, which helps to treat diabetes.

Do NOT use insulin regular innolets if:

  • you are allergic to any ingredient in insulin regular innolets
  • you are having an episode of low blood sugar

Contact your doctor or health care provider right away if any of these apply to you.

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Before using insulin regular innolets:

Some medical conditions may interact with insulin regular innolets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you drink alcoholic beverages or smoke
  • if you have kidney or liver problems; nerve problems; adrenal, pituitary, or thyroid problems; or diabetic ketoacidosis
  • if you use 3 or more insulin injections per day
  • if you are fasting, have high blood sodium levels, or are on a low-salt diet

Some MEDICINES MAY INTERACT with insulin regular innolets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), clonidine, guanethidine, lithium, or reserpine because they may increase the risk of high or low blood sugar or may hide the signs and symptoms of low blood sugar, if it occurs
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), disopyramide, fenfluramine, fibrates (eg, clofibrate, gemfibrozil), fluoxetine, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), oral medicines for diabetes (eg, glipizide, metformin, nateglinide), pentamidine, propoxyphene, salicylates (eg, aspirin), somatostatin analogs (eg, octreotide), or sulfonamide antibiotics (eg, sulfamethoxazole) because the risk of low blood sugar may be increased
  • Corticosteroids (eg, prednisone), danazol, diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, chlorpromazine), progesterones (eg, medroxyprogesterone), somatropin, sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid hormones (eg, levothyroxine) because they may decrease insulin regular innolets's effectiveness, resulting in high blood sugar

This may not be a complete list of all interactions that may occur. Ask your health care provider if insulin regular innolets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use insulin regular innolets:

Use insulin regular innolets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with insulin regular innolets. Talk to your pharmacist if you have questions about this information.
  • Use insulin regular innolets within 30 to 60 minutes before a meal, as directed by your doctor.
  • If you will be using insulin regular innolets at home, a health care provider will teach you how to use it. Be sure you understand how to use insulin regular innolets. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • You may use insulin regular innolets in an insulin pump if you are directed to do so by your doctor. IF you are using an insulin pump do NOT dilute insulin regular innolets or mix it together with any other type of insulin.
  • Insulin regular innolets should be clear and colorless. Do not use insulin regular innolets if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • If you are mixing insulin regular innolets with another insulin, draw insulin regular innolets into the syringe first. Inject the dose immediately after mixing, as directed by your doctor.
  • Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into a vein or muscle.
  • Injection sites within an injection area (abdomen, thigh, upper arm) must be rotated from one injection to the next.
  • Be sure you have purchased the correct insulin. Insulin comes in a variety of containers, including vials, cartridges, and pens. Make sure that you understand how to properly measure and prepare your dose. If you have any questions about measuring and preparing your dose, contact your doctor or pharmacist for information.
  • Insulin regular innolets begins lowering blood sugar within 30 to 60 minutes after an injection. The effects last up to 4 to 12 hours.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • It is very important to follow your insulin regimen exactly. Do NOT miss any doses. Ask your doctor for specific instructions to follow in case you ever miss a dose of insulin.

Ask your health care provider any questions you may have about how to use insulin regular innolets.

Important safety information:

  • Drowsiness, dizziness, blurred vision, or lightheadedness may occur while you use insulin regular innolets. These effects may be worse if you take it with alcohol or certain medicines. Use insulin regular innolets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol without discussing it with your doctor.
  • Inject each dose of insulin in a different area to prevent skin irritation.
  • Illness, especially with nausea and vomiting, may cause your insulin requirements to change. Even if you are not eating, you still require insulin. You and your doctor should establish a sick day plan to use in case of illness. When you are sick, test your blood/urine frequently and call your doctor as instructed.
  • If you will be traveling across more than 2 time zones, consult your doctor concerning adjustments in your insulin schedule.
  • Proper diet, regular exercise, and regular testing of blood sugar are important for best results when using insulin regular innolets. Follow your doctor's instructions carefully. If your blood sugar level is often higher than it should be and you are taking insulin regular innolets according to directions, check with your doctor.
  • Carry an ID card at all times that says you have diabetes.
  • An insulin reaction resulting from low blood sugar levels (hypoglycemia) may occur if you take too much insulin, skip a meal, or exercise too much. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.
  • Developing a fever or infection, eating significantly more than prescribed, or missing your dose of insulin may cause high blood sugar (hyperglycemia). High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Lab tests, such as fasting blood glucose levels or hemoglobin A1c, may be performed while you use insulin regular innolets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use insulin regular innolets with caution in the ELDERLY; if low blood sugar occurs, it may be more difficult to recognize in these patients.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using insulin regular innolets while you are pregnant. It is not known if insulin regular innolets is found in breast milk. If you are or will be breast-feeding while you use insulin regular innolets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of insulin regular innolets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness, swelling, itching, or mild pain at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chills; dizziness; drowsiness; fainting; fast or irregular heartbeat; headache; increased hunger; loss of consciousness; nervousness; seizures; sweating; tremor; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center or emergency room immediately. Symptoms may include chills; dizziness; drowsiness; fainting; headache; increased heartbeat; increased hunger; loss of consciousness; nervousness; seizures; shakiness; sweating; tremor; vision changes; weakness.

Proper storage of insulin regular innolets:

VIALS: Store new (unopened) vials in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store used (open) vials either in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). If refrigeration is not possible, store at room temperature, below 86 degrees F (30 degrees C). Store away from heat and light. If insulin regular innolets has been frozen or overheated, throw it away. Throw away unrefrigerated or opened vials after 28 days, even if they still contain medicine.

INNOLETS and PENFILL CARTRIDGES: Store new (unopened) InnoLets or PenFill cartridges in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store used (open) InnoLets or PenFill cartridges either in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). If refrigeration is not possible, store at room temperature, below 86 degrees F (30 degrees C). Store away from heat and light. If insulin regular innolets has been frozen or overheated, throw it away. Throw away unrefrigerated or opened vials after 28 days, even if they still contain medicine.

Do not leave insulin regular innolets in a car on a warm or sunny day. Do not use insulin regular innolets after the expiration date stamped on the label. Keep insulin regular innolets, as well as syringes and needles, out of the reach of children and away from pets. If you are using insulin regular innolets in an insulin pump, or if insulin regular innolets has been mixed with other medicines or diluted, you may need to store it differently. Ask your doctor, pharmacist, or healthcare provider how to store insulin regular innolets.

General information:

  • If you have any questions about insulin regular innolets, please talk with your doctor, pharmacist, or other health care provider.
  • Insulin regular innolets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about insulin regular innolets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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