Human papillomavirus

Generic Name: human papillomavirus (PAP-i-LO-ma-VYE-rus)
Brand Name: Cervarix

Human papillomavirus is used for:

Preventing certain types of cervical cancer caused by HPV infection in females 10 to 25 years old.

Human papillomavirus is a vaccine. It works by stimulating the body to produce antibodies against HPV infection.

Do NOT use human papillomavirus if:

  • you are allergic to any ingredient in human papillomavirus

Contact your doctor or health care provider right away if this applies to you.

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Before using human papillomavirus:

Some medical conditions may interact with human papillomavirus. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (including latex)
  • if you have or have recently had a fever
  • if you have HIV infection, cancer, a weakened immune system, or you take medicines that affect your immune system
  • if you have bleeding or blood problems (eg, hemophilia, low blood platelet levels)
  • if you are receiving radiation therapy or cancer chemotherapy
  • if you are scheduled to receive any other vaccines
  • if you had an allergic reaction to a previous dose of human papillomavirus

Some MEDICINES MAY INTERACT with human papillomavirus. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alkylating agents (eg, cyclophosphamide), antimetabolites (eg, fluorouracil, methotrexate), corticosteroids (eg, prednisone), or cytotoxics (eg, cisplatin) because they may decrease human papillomavirus's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if human papillomavirus may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use human papillomavirus:

Use human papillomavirus as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with human papillomavirus. Talk to your pharmacist if you have questions about this information.
  • Human papillomavirus is usually given as an injection at your doctor's office, hospital, or clinic.
  • Human papillomavirus is given as a series of 3 separate injections. The first dose is given on a date chosen by you and your doctor. The second dose is given 1 month after the first dose. The third dose is given 6 months after the first dose. Be sure to keep all doctor appointments.
  • If you miss a dose of human papillomavirus, contact your doctor to reschedule your vaccine.

Ask your health care provider any questions you may have about how to use human papillomavirus.

Important safety information:

  • Human papillomavirus may cause dizziness or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use human papillomavirus with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Fainting with jerking movements, seizure-like activity, and falling with injury has occurred following vaccination with human papillomavirus. Your doctor may ask you to sit or lie down for 15 minutes after you receive this vaccine.
  • Human papillomavirus may not provide protection against HPV infection in all recipients. Discuss any questions or concerns with your doctor.
  • Human papillomavirus is only effective against certain types of HPV. Discuss any questions or concerns with your doctor.
  • Human papillomavirus is not a treatment for patients already infected with HPV. It does not cure cervical cancer caused by HPV infection.
  • Human papillomavirus does not prevent or treat diseases that are not caused by HPV.
  • Continue to have regular Pap smears and routine cervical cancer screenings as directed by your doctor, even after you receive human papillomavirus.
  • Human papillomavirus should be used with extreme caution in CHILDREN younger than 10 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use human papillomavirus if you are pregnant. If you think you may be pregnant, tell your doctor before you receive human papillomavirus. It is not known if human papillomavirus is found in breast milk. If you are or will be breast-feeding while you use human papillomavirus, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of human papillomavirus:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; mild fever; mild pain, redness, itching, bruising, or swelling at the injection site; muscle or joint aches; nausea; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting with jerking movements or seizure-like activity.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of human papillomavirus:

Human papillomavirus is usually handled and stored by a health care provider. If you are using human papillomavirus at home, store human papillomavirus as directed by your pharmacist or health care provider. Keep human papillomavirus out of the reach of children and away from pets.

General information:

  • If you have any questions about human papillomavirus, please talk with your doctor, pharmacist, or other health care provider.
  • Human papillomavirus is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take human papillomavirus or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about human papillomavirus. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to human papillomavirus. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using human papillomavirus.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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