Hemin

Generic Name: hemin (HE-min)
Brand Name: Panhematin

Hemin should only be used if other medicines are not tolerated or effective.


Hemin is used for:

Treating symptoms of certain blood disorders (porphyria). It may also be used for other conditions as determined by your doctor.

Hemin is an enzyme inhibitor made from red blood cells. It works by correcting certain types of heme deficiency in the liver.

Do NOT use hemin if:

  • you are allergic to any ingredient in hemin
  • you are taking anticoagulants (eg, warfarin), estrogens, barbiturates (eg, phenobarbital), or steroids (eg, prednisone)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: View Frightful (But Dead Serious) Drug Side Effects

Before using hemin:

Some medical conditions may interact with hemin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have blood clotting disorders

Some MEDICINES MAY INTERACT with hemin. However, no specific interactions with hemin are known at this time.

  • Barbiturates (eg, phenobarbital), estrogens, or steroids (eg, prednisone) because they may decrease hemin's effectiveness
  • Anticoagulants (eg, warfarin) because of the risk of their side effects may be increased by hemin

This may not be a complete list of all interactions that may occur. Ask your health care provider if hemin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use hemin:

Use hemin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Hemin is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions you may have about hemin.
  • Do not use hemin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of hemin, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use hemin.

Important safety information:

  • Hemin is made from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used hemin.
  • Hemin should not be used in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using hemin while you are pregnant. It is not known if hemin is found in breast milk. If you are or will be breast-feeding while you use hemin, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of hemin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild fever; pain, redness, or swelling at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine; unusual bleeding; unusual tiredness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of hemin:

Hemin is usually handled and stored by a health care provider. If you are using hemin at home, store hemin as directed by your pharmacist or health care provider. Keep hemin out of the reach of children and away from pets.

General information:

  • If you have any questions about hemin, please talk with your doctor, pharmacist, or other health care provider.
  • Hemin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take hemin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about hemin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to hemin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using hemin.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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