Guaifenesin/ phenylephrine/ pseudoephedrine liquid

Generic Name: guaifenesin/phenylephrine/pseudoephedrine (gwye-FEN-e-sin/fen-il-EF-rin/sue-doe-e-FED-rin)
Brand Name: Conex

Guaifenesin/ phenylephrine/ pseudoephedrine liquid is used for:

Relieving symptoms of congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Guaifenesin/phenylephrine/pseudoephedrine liquid is a decongestant and expectorant combination. It works by constricting blood vessels and shrinking swollen and congested nasal tissues (mucous membranes) and by thinning and loosening mucus in the airway. This allows you to breathe more easily and makes coughs more productive.

Do NOT use guaifenesin/ phenylephrine/ pseudoephedrine liquid if:

  • you are allergic to any ingredient in guaifenesin/phenylephrine/pseudoephedrine liquid
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

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Before using guaifenesin/ phenylephrine/ pseudoephedrine liquid:

Some medical conditions may interact with guaifenesin/phenylephrine/pseudoephedrine liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, an enlarged prostate or other prostate problems, seizures, or an overactive thyroid
  • if you have chronic cough

Some MEDICINES MAY INTERACT with guaifenesin/phenylephrine/pseudoephedrine liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects of guaifenesin/phenylephrine/pseudoephedrine liquid may be increased
  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine because side effects may be increased by guaifenesin/phenylephrine/pseudoephedrine liquid
  • Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by guaifenesin/phenylephrine/pseudoephedrine liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if guaifenesin/phenylephrine/pseudoephedrine liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use guaifenesin/ phenylephrine/ pseudoephedrine liquid:

Use guaifenesin/phenylephrine/pseudoephedrine liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Guaifenesin/phenylephrine/pseudoephedrine liquid may be taken with or without food.
  • Take guaifenesin/phenylephrine/pseudoephedrine liquid with a full glass of water unless your doctor directs otherwise.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of guaifenesin/phenylephrine/pseudoephedrine liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use guaifenesin/phenylephrine/pseudoephedrine liquid.

Important safety information:

  • Guaifenesin/phenylephrine/pseudoephedrine liquid may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to guaifenesin/phenylephrine/pseudoephedrine liquid. Using guaifenesin/phenylephrine/pseudoephedrine liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not take diet or appetite control medicines while you are taking guaifenesin/phenylephrine/pseudoephedrine liquid without checking with you doctor.
  • Do NOT exceed the recommended dose or use/take guaifenesin/phenylephrine/pseudoephedrine liquid for longer than prescribed without checking with your doctor.
  • Guaifenesin/phenylephrine/pseudoephedrine liquid contains phenylephrine and pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine or pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
  • Guaifenesin/phenylephrine/pseudoephedrine liquid may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking guaifenesin/phenylephrine/pseudoephedrine liquid.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using guaifenesin/phenylephrine/pseudoephedrine liquid.
  • Use guaifenesin/phenylephrine/pseudoephedrine liquid with caution in the ELDERLY because they may be more sensitive to its effects.
  • Caution is advised when using guaifenesin/phenylephrine/pseudoephedrine liquid in CHILDREN because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking guaifenesin/phenylephrine/pseudoephedrine liquid, discuss with your doctor the benefits and risks of using guaifenesin/phenylephrine/pseudoephedrine liquid during pregnancy. It is unknown if guaifenesin/phenylephrine/pseudoephedrine liquid is excreted in breast milk. Do not breast-feed while taking guaifenesin/phenylephrine/pseudoephedrine liquid.

Possible side effects of guaifenesin/ phenylephrine/ pseudoephedrine liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of guaifenesin/phenylephrine/pseudoephedrine liquid:

Store guaifenesin/phenylephrine/pseudoephedrine liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep guaifenesin/phenylephrine/pseudoephedrine liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about guaifenesin/phenylephrine/pseudoephedrine liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Guaifenesin/phenylephrine/pseudoephedrine liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about guaifenesin/phenylephrine/pseudoephedrine liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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