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Fosfomycin

Pronunciation

Generic Name: fosfomycin (FOS-foe-MYE-sin)
Brand Name: Monurol

Fosfomycin is used for:

Treating uncomplicated urinary tract infections in women caused by certain bacteria.

Fosfomycin is an anti-infective. It works by killing sensitive bacteria.

Do NOT use fosfomycin if:

  • you are allergic to any ingredient in fosfomycin

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: 10 Things to Know About Antibiotic Resistance

Before using fosfomycin:

Some medical conditions may interact with fosfomycin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems or asthma

Some MEDICINES MAY INTERACT with fosfomycin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anorexiants (eg, phentermine) or certain sympathomimetics (eg, albuterol, amphetamine, pseudoephedrine) because the risk of their side effects may be increased by fosfomycin
  • Lithium or tetracyclines because their effectiveness may be decreased by fosfomycin
  • Metoclopramide because it may decrease fosfomycin's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if fosfomycin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use fosfomycin:

Use fosfomycin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take fosfomycin by mouth with or without food.
  • To take fosfomycin, dissolve the contents of 1 packet in 3 to 4 ounces of water and drink immediately. Do not mix with hot water. Do not take fosfomycin in its dry form.
  • If you are also taking a tetracycline (eg, doxycycline), take it at least 2 hours before or after you take fosfomycin.
  • Only one dose of fosfomycin is necessary. If you forget to take fosfomycin, take it as soon as you remember.

Ask your health care provider any questions you may have about how to use fosfomycin.

Important safety information:

  • Fosfomycin may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to fosfomycin. Using fosfomycin alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • If your symptoms do not get better within 2 to 3 days or if they get worse, check with your doctor.
  • Lab tests, including complete blood cell counts, may be performed while you use fosfomycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Fosfomycin should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using fosfomycin while you are pregnant. It is not known if fosfomycin is found in breast milk. Do not breast-feed while taking fosfomycin.

Possible side effects of fosfomycin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; headache; indigestion; loss of appetite; nausea; painful menstruation; runny nose; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody diarrhea; changes in vision; severe diarrhea; severe stomach cramps or pain; vaginal irritation or discharge; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of fosfomycin:

Store fosfomycin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep fosfomycin out of the reach of children and away from pets.

General information:

  • If you have any questions about fosfomycin, please talk with your doctor, pharmacist, or other health care provider.
  • Fosfomycin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take fosfomycin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about fosfomycin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to fosfomycin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using fosfomycin.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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