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Extendryl PSE extended-release tablets

Generic Name: methscopolamine/pseudoephedrine (meth-skoe-POL-a-meen/soo-doe-e-FED-rin)
Brand Name: Examples include Amdry-D and Extendryl PSE

Extendryl PSE extended-release tablets is used for:

Relieving congestion due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Extendryl PSE extended-release tablets is a decongestant and anticholinergic combination. It works by relieving nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and decreasing lung secretions, which dries the chest.

Do NOT use Extendryl PSE extended-release tablets if:

  • you are allergic to any ingredient in Extendryl PSE extended-release tablets or to similar medicines (eg, ephedrine)
  • you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
  • you have severe heart blood vessel disease; severe high blood pressure; severe heart problems; a rapid heartbeat; narrow-angle glaucoma; severe or uncontrolled bleeding; severe irritation of the esophagus or other serious problems with the esophagus (eg, esophageal achalasia); peptic ulcer; a blockage of your stomach, bowel, or bladder; bowel motility problems; severe bowel inflammation (eg, ulcerative colitis); or certain muscle problems (eg, myasthenia gravis)
  • you are unable to urinate or you are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Video: Asthma

How to prevent and treat an asthma attack.

Before using Extendryl PSE extended-release tablets:

Some medical conditions may interact with Extendryl PSE extended-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of diabetes, an enlarged prostate or other prostate problems, bladder or kidney problems, severe bowel problems, high blood pressure, asthma, nerve problems, heart problems, blood vessel problems, blood clots, trouble urinating, a hiatal hernia, an adrenal gland tumor, glaucoma or increased eye pressure, breathing problems during sleep, stroke, seizures, or an overactive thyroid
  • if you have diarrhea

Some MEDICINES MAY INTERACT with Extendryl PSE extended-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or methyldopa because the risk of severe high blood pressure, fever, fast heartbeat, and seizures may be increased
  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Anticholinergic medicines (eg, benztropine, hyoscyamine, trihexyphenidyl), certain medicines for mental or mood disorders (eg, thioridazine), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Extendryl PSE extended-release tablets's side effects
  • Bromocriptine because the risk of its side effects may be increased by Extendryl PSE extended-release tablets
  • Guanadrel, guanethidine, mecamylamine, or reserpine because their effectiveness may be decreased by Extendryl PSE extended-release tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Extendryl PSE extended-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Extendryl PSE extended-release tablets:

Use Extendryl PSE extended-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Extendryl PSE extended-release tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow Extendryl PSE extended-release tablets whole. Do not break, crush, or chew before swallowing. Some brands of Extendryl PSE extended-release tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
  • If you miss a dose of Extendryl PSE extended-release tablets and you are taking it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Extendryl PSE extended-release tablets.

Important safety information:

  • Extendryl PSE extended-release tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Extendryl PSE extended-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If your symptoms do not get better within 7 days or if they get worse, or if you develop a high fever or persistent headache, check with your doctor.
  • Extendryl PSE extended-release tablets may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate).
  • Extendryl PSE extended-release tablets may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Extendryl PSE extended-release tablets may reduce sweating. Do not become overheated in hot weather or during exercise or other activities; heatstroke may occur.
  • Do not take diet or appetite control medicines while you are taking Extendryl PSE extended-release tablets without checking with your doctor first.
  • Extendryl PSE extended-release tablets has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Extendryl PSE extended-release tablets.
  • Tell your doctor or dentist that you take Extendryl PSE extended-release tablets before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Extendryl PSE extended-release tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Extendryl PSE extended-release tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Extendryl PSE extended-release tablets.
  • Use Extendryl PSE extended-release tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Extendryl PSE extended-release tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Extendryl PSE extended-release tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Extendryl PSE extended-release tablets while you are pregnant. Extendryl PSE extended-release tablets is found in breast milk. Do not breast-feed while taking Extendryl PSE extended-release tablets.

Possible side effects of Extendryl PSE extended-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; restlessness; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing.

Proper storage of Extendryl PSE extended-release tablets:

Store Extendryl PSE extended-release tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Extendryl PSE extended-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Extendryl PSE extended-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Extendryl PSE extended-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Extendryl PSE extended-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Extendryl PSE extended-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Extendryl PSE extended-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Extendryl PSE extended-release tablets.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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