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Extendryl chewable tablets

Generic Name: chlorpheniramine/phenylephrine/methscopolamine (KLOR-fen-IR-a-meen/FEN-il-EF-rin/METH-skoe-POL-a-meen)
Brand Name: Examples include AH-Chew and Extendryl

Extendryl chewable tablets is used for:

Relieving congestion, sneezing, runny nose, and itchy, watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Extendryl chewable tablets is an antihistamine, decongestant, and anticholinergic combination. It works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also relieves nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and dries the chest by decreasing lung secretions.

Do NOT use Extendryl chewable tablets if:

  • you are allergic to any ingredient in Extendryl chewable tablets
  • you are pregnant or breast-feeding
  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
  • you are taking or have taken medicine for high blood pressure or depression in the last 14 days
  • you have a history of narrow-angle glaucoma, blockage in the stomach or intestines, peptic ulcer disease, intestinal or bowel problems, difficulty urinating, inflammation of the esophagus from reflux disease, difficulty swallowing, or uncontrolled bleeding
  • you have severe heart disease or severe high blood pressure

Contact your doctor or health care provider right away if any of these apply to you.

Video: Asthma

How to prevent and treat an asthma attack.

Before using Extendryl chewable tablets:

Some medical conditions may interact with Extendryl chewable tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diabetes, an enlarged prostate, a history of bladder or kidney problems, high blood pressure, diarrhea, asthma, nerve problems, heart problems, blood clots, a hiatal hernia, an adrenal gland tumor, glaucoma, breathing problems during sleep, myasthenia gravis (muscle weakness), or an overactive thyroid

Some MEDICINES MAY INTERACT with Extendryl chewable tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alpha-blockers (eg, guanethidine, methyldopa, prazosin), beta-blockers (eg, atenolol), diuretics (eg, furosemide, hydrochlorothiazide), furazolidone, or MAOIs (eg, phenelzine) because the risk of high or low blood pressure may be increased
  • Alkalizers (eg, calcium or magnesium antacids), anticholinergics (eg, atropine, benztropine, dicyclomine), carbonic anhydrase inhibitors (eg, acetazolamide), ergotamine, sodium bicarbonate, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Extendryl chewable tablets's side effects
  • Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), certain stimulants (eg, doxapram, pseudoephedrine), cocaine, digoxin, droxidopa, potassium chloride, or sodium oxybate (GHB) because the risk of their side effects may be increased by Extendryl chewable tablets
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Extendryl chewable tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Extendryl chewable tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Extendryl chewable tablets:

Use Extendryl chewable tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Extendryl chewable tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Do not take Extendryl chewable tablets at the same time as antacids, certain medicines for diarrhea (eg, attapulgite, bismuth, kaolin, pectin), or ketoconazole. Take these medicines 2 or 3 hours before or after you take Extendryl chewable tablets.
  • Chew thoroughly before swallowing. Follow with a glass of water.
  • If you miss a dose of Extendryl chewable tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Extendryl chewable tablets.

Important safety information:

  • Extendryl chewable tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Extendryl chewable tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Extendryl chewable tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • If your symptoms do not get better within 7 days or if they get worse or you develop a high fever or persistent headache, check with your doctor.
  • Extendryl chewable tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know that you are taking Extendryl chewable tablets.
  • Extendryl chewable tablets may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Extendryl chewable tablets may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
  • Extendryl chewable tablets may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Do not take diet or appetite control medicines while you are taking Extendryl chewable tablets without checking with your doctor.
  • If you have trouble sleeping, ask your doctor or pharmacist about the best time of day to take Extendryl chewable tablets.
  • Diabetes patients - Extendryl chewable tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Use Extendryl chewable tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Extendryl chewable tablets should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Extendryl chewable tablets if you are pregnant. If you think you may be pregnant, contact your doctor right away. Do not use Extendryl chewable tablets during labor or delivery because it could cause harm to the fetus. Extendryl chewable tablets is found in breast milk. Do not breast-feed while taking Extendryl chewable tablets.

Possible side effects of Extendryl chewable tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; clumsiness; constipation; dizziness; drowsiness; dry mouth, nose, or throat; excitability or irritability (especially in children); flushing; giddiness; headache; lack of energy; nausea; nervousness; tearing; trouble sleeping; unusual tiredness or weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; mental or mood changes; pounding in the chest; unusual bleeding or bruising; urinary retention; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include convulsions; deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing; vomiting.

Proper storage of Extendryl chewable tablets:

Store Extendryl chewable tablets in a tightly closed container between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Extendryl chewable tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Extendryl chewable tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Extendryl chewable tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Extendryl chewable tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Extendryl chewable tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Extendryl chewable tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Extendryl chewable tablets.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Watch this video series to learn about managing severe allergies (anaphylaxis).

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