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Doxycycline hyclate delayed-release tablets

Pronunciation

Generic Name: doxycycline hyclate (DOX-i-SYE-kleen HYE-klate)
Brand Name: Doryx

Doxycycline hyclate delayed-release tablets is used for:

Treating certain bacterial infections. It may be used in combination with other medicines to treat acne or certain amoeba infections. It may be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months. It may also be used to prevent or slow the progression of anthrax after exposure.

Doxycycline hyclate delayed-release tablets is a tetracycline antibiotic. It works by slowing the growth of bacteria. Slowing the bacteria's growth allows the body's immune system to destroy the bacteria.

Do NOT use doxycycline hyclate delayed-release tablets if:

  • you are allergic to any ingredient in doxycycline hyclate delayed-release tablets or to another tetracycline (eg, minocycline)
  • you are taking acitretin, isotretinoin, or a penicillin (eg, amoxicillin)
  • you have recently received or will be receiving a live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

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Before using doxycycline hyclate delayed-release tablets:

Some medical conditions may interact with doxycycline hyclate delayed-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a history of lupus, or the blood disease porphyria
  • if you are on a low-sodium (salt) diet

Some MEDICINES MAY INTERACT with doxycycline hyclate delayed-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), iron, or urinary alkalinizers (eg, sodium bicarbonate) because they may decrease doxycycline hyclate delayed-release tablets's effectiveness
  • Acitretin, anticoagulants (eg, warfarin), digoxin, isotretinoin, methotrexate, or methoxyflurane because the risk of their side effects may be increased by doxycycline hyclate delayed-release tablets
  • Live oral typhoid vaccine, hormonal birth control (eg, birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by doxycycline hyclate delayed-release tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if doxycycline hyclate delayed-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use doxycycline hyclate delayed-release tablets:

Use doxycycline hyclate delayed-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take doxycycline hyclate delayed-release tablets by mouth with or without food. If stomach upset occurs, take with food or milk to reduce stomach irritation.
  • Swallow doxycycline hyclate delayed-release tablets whole. Do not crush or chew before swallowing.
  • Drink plenty of fluids with doxycycline hyclate delayed-release tablets to wash it down. This will also help to decrease the risk of throat irritation from doxycycline hyclate delayed-release tablets.
  • If you have trouble swallowing doxycycline hyclate delayed-release tablets whole, you may carefully break up the tablet and sprinkle it on a spoonful of smooth applesauce. Do not crush or damage the beads in this tablet. Do not use hot applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. Do not chew the mixture. Do not store the mixture for use at a later time.
  • Do not take an antacid that has aluminum, calcium, or magnesium in it; bismuth-containing products; urinary alkalinizers (eg, sodium bicarbonate); or multivitamins with minerals within 2 hours before or after you take doxycycline hyclate delayed-release tablets.
  • To clear up your infection completely, take doxycycline hyclate delayed-release tablets for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you are taking doxycycline hyclate delayed-release tablets to prevent malaria, you should begin to take it 1 to 2 days before you travel to the malaria-infected area. You will need to keep taking it for 4 weeks after you leave the area. Discuss any questions with your doctor.
  • Do not use doxycycline hyclate delayed-release tablets if it is outdated or has been stored incorrectly.
  • If you miss a dose of doxycycline hyclate delayed-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use doxycycline hyclate delayed-release tablets.

Important safety information:

  • Be sure to use doxycycline hyclate delayed-release tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Doxycycline hyclate delayed-release tablets only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of doxycycline hyclate delayed-release tablets may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • If you are taking doxycycline hyclate delayed-release tablets to prevent malaria, please note that no malaria medicine, including doxycycline hyclate delayed-release tablets, guarantees protection against malaria. Stay in well-screened areas, use mosquito nets, cover the body with clothing, and use insect repellent to avoid being bitten by mosquitoes.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using doxycycline hyclate delayed-release tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Doxycycline hyclate delayed-release tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to doxycycline hyclate delayed-release tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or blood stools occur. Do not treat diarrhea without first checking with your doctor.
  • Do not use more than the recommended dose or use doxycycline hyclate delayed-release tablets for longer than prescribed without checking with your doctor.
  • Tell your doctor or dentist that you take doxycycline hyclate delayed-release tablets before you receive any medical or dental care, emergency care, or surgery.
  • Doxycycline hyclate delayed-release tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking doxycycline hyclate delayed-release tablets.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use doxycycline hyclate delayed-release tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Doxycycline hyclate delayed-release tablets should not be used in CHILDREN younger than 8 years old; permanent yellow-gray-brown tooth discoloration may occur.
  • PREGNANCY and BREAST-FEEDING: Doxycycline hyclate delayed-release tablets has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using doxycycline hyclate delayed-release tablets while you are pregnant. Doxycycline hyclate delayed-release tablets is found in breast milk. Do not breast-feed while taking doxycycline hyclate delayed-release tablets.

Possible side effects of doxycycline hyclate delayed-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Loss of appetite; nausea; sensitivity to sunlight; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; red, swollen, blistered, or peeling skin; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of doxycycline hyclate delayed-release tablets:

Store doxycycline hyclate delayed-release tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep doxycycline hyclate delayed-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about doxycycline hyclate delayed-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Doxycycline hyclate delayed-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take doxycycline hyclate delayed-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about doxycycline hyclate delayed-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to doxycycline hyclate delayed-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using doxycycline hyclate delayed-release tablets.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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