Generic Name: cabergoline (ka-BER-goe-leen)
Brand Name: Generic only. No brands available.
Dostinex is used for:
Treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. It may also be used for other conditions as determined by your doctor.
Dostinex is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.
Do NOT use Dostinex if:
- you are allergic to any ingredient in Dostinex or to ergot derivatives (eg, ergotamine)
- you have uncontrolled high blood pressure
- you have a history of heart valve problems or certain fibrotic (scarring) disorders (eg, of the lung, heart, kidneys)
- you are taking a butyrophenone (eg, haloperidol), metoclopramide, a phenothiazine (eg, chlorpromazine), or a thioxanthene (eg, thiothixene)
- you have taken or will be taking a "triptan" (eg, sumatriptan) within 24 hours before or after taking Dostinex
Contact your doctor or health care provider right away if any of these apply to you.
Before using Dostinex:
Some medical conditions may interact with Dostinex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver problems or high blood pressure
- if you have developed high blood pressure caused by pregnancy
- if you take any medicine that may lower blood pressure or cause heart valve problems. Check with your doctor or pharmacist if you are unsure if any of your medicines may lower blood pressure or cause heart valve problems
Some MEDICINES MAY INTERACT with Dostinex. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Macrolides (eg, clarithromycin) because they may increase the risk of Dostinex's side effects
- Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Dostinex's effectiveness
- "Triptans" (eg, sumatriptan) because the risk of their side effects may be increased by Dostinex
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dostinex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Dostinex:
Use Dostinex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Dostinex by mouth with or without food.
- It may be helpful to mark on a calendar which days you are supposed to take Dostinex.
- If you miss a dose of Dostinex, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Dostinex.
Important safety information:
- Dostinex may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Dostinex with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Dostinex may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Some patients taking Dostinex have developed certain behavioral changes (eg, increased gambling or sexual urges). These effects usually go away when treatment with Dostinex is stopped. Contact your doctor right away if you notice any unusual behavioral changes.
- If you think you may be pregnant, contact your doctor so that a pregnancy test can be arranged.
- Lab tests, including chest x-rays, blood prolactin levels, and heart and kidney function, may be performed while you use Dostinex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Dostinex should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dostinex while you are pregnant. It is not known if Dostinex is found in breast milk. Do not breast-feed while taking Dostinex.
Possible side effects of Dostinex:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; dizziness; headache; indigestion; mild stomach pain; nausea; tiredness or weakness; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; behavior changes (eg, aggression, increased gambling or sexual urges); burning, numbness, or tingling; chest pain; confusion; decreased urination; fainting; hallucinations; irregular heartbeat; mood or mental changes (eg, depression); persistent cough; severe or persistent dizziness or light-headedness; severe stomach pain or tenderness; shortness of breath; sudden, unexplained weight gain; swelling of hands, ankles, legs, or feet; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; hallucinations; nasal congestion.Proper storage of Dostinex:
Store Dostinex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dostinex out of the reach of children and away from pets.
- If you have any questions about Dostinex, please talk with your doctor, pharmacist, or other health care provider.
- Dostinex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Dostinex or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Dostinex. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Dostinex. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Dostinex.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.