Dopamine

Pronunciation

Generic Name: dopamine (DOE-pa-meen)
Brand Name: Generic only. No brands available.

Dopamine is used for:

Treating shock and low blood pressure due to heart attack, trauma, infections, surgery, and other causes. It is also used to help improve heart function when it is unable to pump enough blood. It may also be used for other conditions as determined by your doctor.

Dopamine is a vasopressor and inotropic agent. It works by increasing the pumping strength of the heart and the kidney blood supply.

Do NOT use dopamine if:

  • you are allergic to any ingredient in dopamine
  • you are taking droxidopa or have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 21 days
  • you have adrenal gland tumors or an uncorrected irregular heartbeat

Contact your doctor or health care provider right away if any of these apply to you.

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Before using dopamine:

Some medical conditions may interact with dopamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (eg, sulfites)
  • if you have diabetes, a history of high blood pressure or heart attacks, a history of blood vessel disease (arteriosclerosis, Raynaud disease, Buerger disease), or a decreased amount of blood in the body (hypovolemia)

Some MEDICINES MAY INTERACT with dopamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone) because the side effects of dopamine may be increased
  • Cyclopropane, droxidopa, ergot derivatives (eg, methylergonovine), furazolidone, halogenated hydrocarbon anesthetics (eg, halothane), or MAO inhibitors (eg, phenelzine) because the risk of side effects, such as irregular heartbeat, heart attack, or seizures, may be increased
  • Alpha-blockers (eg, prazosin), beta-blockers (eg, propranolol), butyrophenones (eg, haloperidol), hydantoins (eg, phenytoin), or phenothiazines because the effectiveness of dopamine may be decreased
  • Bromocriptine or tricyclic antidepressants (eg, amitriptyline) because their side effects may be increased
  • Guanadrel or guanethidine because their effectiveness may be decreased by dopamine

This may not be a complete list of all interactions that may occur. Ask your health care provider if dopamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use dopamine:

Use dopamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Dopamine is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using dopamine at home, carefully follow the injection procedures taught to you by your health care provider.
  • If dopamine contains particles or is discolored (darker than slightly yellow), or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of dopamine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use dopamine.

Important safety information:

  • Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.
  • LAB TESTS, including urine output, heart function, blood pressure, and thyroid tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking dopamine, discuss with your doctor the benefits and risks of using dopamine during pregnancy. It is unknown if dopamine is excreted in breast milk. If you are or will be breast-feeding while you are using dopamine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of dopamine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Fast heartbeat; headache; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dizziness; irregular heartbeat; pain, redness, or swelling at the injection site; severe headache.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fast or irregular heartbeat; inability to urinate; nausea; severe headache; vomiting.

Proper storage of dopamine:

Dopamine is usually handled and stored by a health care provider. If you are using dopamine at home, store dopamine as directed by your pharmacist or health care provider.

General information:

  • If you have any questions about dopamine, please talk with your doctor, pharmacist, or other health care provider.
  • Dopamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take dopamine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about dopamine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to dopamine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using dopamine.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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