Dipivefrin

Generic Name: dipivefrin (dye-PI-ve-frin)
Brand Name: Propine

Dipivefrin is used for:

Controlling inner eye pressure in patients with open-angle glaucoma. It may also be used for other conditions as determined by your doctor.

Dipivefrin is a sympathomimetic. It works by decreasing fluid formation inside the eyeball and increasing fluid drainage from the eyeball, which helps lower pressure inside the eye.

Do NOT use dipivefrin if:

  • you are allergic to any ingredient in dipivefrin
  • you have narrow-angle glaucoma
  • you are taking a beta-blocker (eg, propranolol)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using dipivefrin:

Some medical conditions may interact with dipivefrin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have other eye problems (eg, lens of your eye has been removed)

Some MEDICINES MAY INTERACT with dipivefrin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol) because the risk for side effects such as increased blood pressure or slow heartbeat may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if dipivefrin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use dipivefrin:

Use dipivefrin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • To use dipivefrin, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • If you miss a dose of dipivefrin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use dipivefrin.

Important safety information:

  • Dipivefrin may cause blurred vision or sensitivity to light. Make sure your vision is clear before driving, operating machinery, or doing anything else that could be dangerous until you know how you react to dipivefrin. Using dipivefrin alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Use dipivefrin with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using dipivefrin during pregnancy. It is unknown if dipivefrin is excreted in breast milk. If you are or will be breast feeding while you are using dipivefrin, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of dipivefrin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; burning; eye redness; headache; itching; sensitivity to light; stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decrease in vision; eye pain; fast heartbeat; irregular heartbeat; swelling of the eye or eyelids.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of dipivefrin:

Store dipivefrin at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep dipivefrin out of the reach of children and away from pets.

General information:

  • If you have any questions about dipivefrin, please talk with your doctor, pharmacist, or other health care provider.
  • Dipivefrin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about dipivefrin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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