Generic Name: diphenhydramine (DYE-fen-HYE-dra-meen)
Brand Name: Benadryl
Diphenhydramine solution is used for:
Treating allergic reactions, allergy symptoms, motion sickness, and Parkinson disease when treatment with medicine taken by mouth is not possible. It may also be used for certain conditions as determined by your doctor.
Diphenhydramine solution is an antihistamine and anticholinergic. It works by blocking the action of histamine, which reduces the symptoms of an allergic reaction. It also works in the brain to reduce symptoms of Parkinson disease and motion sickness.
Do NOT use diphenhydramine solution if:
- you are allergic to any ingredient in diphenhydramine solution or to similar medicines
- you are taking sodium oxybate (GHB)
- you are breast-feeding
Contact your doctor or health care provider right away if any of these apply to you.
Before using diphenhydramine solution:
Some medical conditions may interact with diphenhydramine solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, lung disease, shortness of breath, or sleep apnea
- if you have blockage of the stomach, intestine, or urinary tract; difficulty urinating; diabetes; ulcers; enlargement of the prostate; glaucoma; heart disease; high blood pressure; the blood disease porphyria; or thyroid disease
Some MEDICINES MAY INTERACT with diphenhydramine solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur
This may not be a complete list of all interactions that may occur. Ask your health care provider if diphenhydramine solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use diphenhydramine solution:
Use diphenhydramine solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Diphenhydramine solution is for injection only.
- Diphenhydramine solution is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using diphenhydramine solution at home, a health care provider will teach you how to use it. Be sure you understand how to use diphenhydramine solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use diphenhydramine solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of diphenhydramine solution and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use diphenhydramine solution.
Important safety information:
- Diphenhydramine solution may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use diphenhydramine solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using diphenhydramine solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Diphenhydramine solution may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- Diphenhydramine solution may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to diphenhydramine solution. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Diphenhydramine solution has diphenhydramine in it. Before you start any new medicine, check the label to see if it has diphenhydramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Use diphenhydramine solution with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
- Diphenhydramine solution should not be used in PREMATURE INFANTS or NEWBORNS younger than 4 weeks old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using diphenhydramine solution while you are pregnant. Diphenhydramine solution is found in breast milk. Do not breast-feed while taking diphenhydramine solution.
Possible side effects of diphenhydramine solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; excitability; fast heartbeat; hallucinations; pain, redness, or swelling at the injection site; tightness or pounding in the chest; tremor; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.Proper storage of diphenhydramine solution:
Store diphenhydramine solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep diphenhydramine solution out of the reach of children and away from pets.
- If you have any questions about diphenhydramine solution, please talk with your doctor, pharmacist, or other health care provider.
- Diphenhydramine solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take diphenhydramine solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about diphenhydramine solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to diphenhydramine solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using diphenhydramine solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.