Generic Name: difluprednate (DYE-floo-PRED-nate)
Brand Name: Durezol
Difluprednate emulsion is used for:
Treating swelling, pain, redness, or irritation of the eye after eye surgery. It is also used to treat uveitis (inflammation of the eye).
Difluprednate emulsion is an ophthalmic corticosteroid. It decreases inflammation (eg, pain, redness, swelling, warmth) of the eye.
Do NOT use difluprednate emulsion if:
- you are allergic to any ingredient in difluprednate emulsion
- you have a viral eye infection (eg, herpes, smallpox or vaccinia, chickenpox or varicella) or certain other eye infections (eg, bacterial, fungal, mycobacterial)
Contact your doctor or health care provider right away if any of these apply to you.
Before using difluprednate emulsion:
Some medical conditions may interact with difluprednate emulsion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you wear soft contact lenses
- if you have diabetes, eye discharge, thinning of the cornea or sclera, glaucoma, or increased eye pressure
- if you are planning to have or have recently had cataract surgery
- if you have a history of herpes infection of the eye
Some MEDICINES MAY INTERACT with difluprednate emulsion. However, no specific interactions with difluprednate emulsion are known at this time.
Ask your health care provider if difluprednate emulsion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use difluprednate emulsion:
Use difluprednate emulsion as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Difluprednate emulsion is only for the eye. Do not get it in your nose or mouth.
- Shake well before each use.
- If you wear contact lenses, remove them before you use difluprednate emulsion. Soft contact lenses may absorb a chemical in difluprednate emulsion. Wait 10 minutes after you use difluprednate emulsion before you put your contacts back in.
- To use difluprednate emulsion in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- If you will be using difluprednate emulsion to treat both eyes after surgery, do not use the same bottle for both eyes. Doing so may increase the risk of passing an infection from 1 eye to the other.
- If you miss a dose of difluprednate emulsion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use difluprednate emulsion.
Important safety information:
- Difluprednate emulsion may cause blurred vision. Use difluprednate emulsion with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor. Prolonged use of difluprednate emulsion may increase the risk of glaucoma. If you use difluprednate emulsion for 10 days or longer, your eyes will need to be rechecked by your eye care provider.
- If your symptoms do not get better within 2 days or if they get worse, check with your eye doctor.
- Lab tests, including eye exams, may be performed while you use difluprednate emulsion. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Difluprednate emulsion should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using difluprednate emulsion while you are pregnant. It is not known if difluprednate emulsion is found in breast milk. If you are or will be breast-feeding while you use difluprednate emulsion, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of difluprednate emulsion:
All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with difluprednate emulsion. Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision (eg, blurred vision, decreased vision); continued or worsening itching, tearing, or irritation; delayed healing after surgery; discharge from the eye; eye pain; feeling of having something in your eye; new or worsening redness, inflammation, or swelling of the eye or eyelid; sensitivity to light.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of difluprednate emulsion:
Store difluprednate emulsion at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store in an upright position. Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep difluprednate emulsion out of the reach of children and away from pets.
- If you have any questions about difluprednate emulsion, please talk with your doctor, pharmacist, or other health care provider.
- Difluprednate emulsion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take difluprednate emulsion or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about difluprednate emulsion. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to difluprednate emulsion. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using difluprednate emulsion.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.