Despec NR Drops

Generic Name: phenylephrine/dextromethorphan/guaifenesin (FEN-il-EF-rin/DEX-troe-meth-OR-fan/gwye-FEN-e-sin)
Brand Name: Examples include Despec NR Drops and Zotex Pediatric Drops

Despec NR Drops is used for:

Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Despec NR Drops is a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels, reducing swelling in the nasal passages, and loosening mucus and lung secretions in the chest, making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Despec NR Drops if:

  • you are allergic to any ingredient in Despec NR Drops
  • you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
  • you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

Before using Despec NR Drops:

Some medical conditions may interact with Despec NR Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of glaucoma, enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, mental or mood problems (eg, depression), an overactive thyroid, seizures, or stroke
  • if you have a chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus
  • if you are in poor health or are very overweight

Some MEDICINES MAY INTERACT with Despec NR Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Despec NR Drops's side effects
  • Bromocriptine because the risk of its side effects may be increased by Despec NR Drops
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Despec NR Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Despec NR Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Despec NR Drops:

Use Despec NR Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Despec NR Drops by mouth with or without food.
  • Use the dropper that comes with Despec NR Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Take Despec NR Drops with a full glass of water (8 oz/240 mL).
  • Drink plenty of water while taking Despec NR Drops.
  • If you miss a dose of Despec NR Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Despec NR Drops.

Important safety information:

  • Despec NR Drops may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Despec NR Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Despec NR Drops has phenylephrine and dextromethorphan in it. Before you start any new medicine, check the label to see if it has phenylephrine or dextromethorphan in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take Despec NR Drops for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor or pharmacist.
  • Do not use Despec NR Drops for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Despec NR Drops may interfere with certain lab tests. Be sure that your doctor and lab personnel know you are taking Despec NR Drops.
  • Tell your doctor or dentist that you take Despec NR Drops before you receive any medical or dental care, emergency care, or surgery.
  • Use Despec NR Drops with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: It is not known if Despec NR Drops can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Despec NR Drops while you are pregnant. It is not known if Despec NR Drops is found in breast milk. Do not breast-feed while taking Despec NR Drops.

Possible side effects of Despec NR Drops:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; excitability; headache; irritability; nausea; stomach upset; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast, slow, or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, anxiety, nervousness); paleness; seizures; severe or persistent dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; difficulty urinating; fast or shallow breathing; hallucinations; paleness; restlessness; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Despec NR Drops:

Store Despec NR Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Despec NR Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Despec NR Drops, please talk with your doctor, pharmacist, or other health care provider.
  • Despec NR Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Despec NR Drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Despec NR Drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Despec NR Drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Despec NR Drops.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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