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Depo-Provera injectable suspension

Pronunciation

Generic Name: medroxyprogesterone (meh-DROX-ee-pro-JESS-tuh-rone)
Brand Name: Depo-Provera

Depo-Provera injectable suspension is used for:

Treating certain types of endometrial cancer or kidney cancer that cannot be treated with surgery. It may also be used along with other medicines.

Depo-Provera injectable suspension is a progestin hormone. Exactly how Depo-Provera injectable suspension works to treat these conditions is unknown.

Do NOT use Depo-Provera injectable suspension if:

  • you are allergic to any ingredient in Depo-Provera injectable suspension
  • you have a history of bleeding in the brain or stroke, brain blood vessel problems, breast cancer, liver problems, undiagnosed vaginal bleeding, or blood clots
  • you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Before using Depo-Provera injectable suspension:

Some medical conditions may interact with Depo-Provera injectable suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of an abnormal mammogram, fibrocystic breast disease, lumps in the breast, bleeding from your nipples, kidney problems, high blood pressure, migraine headaches, asthma, seizures, diabetes, or mental or mood problems (eg, depression)
  • if you have a family history of breast cancer

Some MEDICINES MAY INTERACT with Depo-Provera injectable suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglutethimide or rifampin because it may decrease Depo-Provera injectable suspension's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Depo-Provera injectable suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Depo-Provera injectable suspension:

Use Depo-Provera injectable suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Depo-Provera injectable suspension. Talk to your pharmacist if you have questions about this information.
  • Depo-Provera injectable suspension is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Depo-Provera injectable suspension at home, a health care provider will teach you how to use it. Be sure you understand how to use Depo-Provera injectable suspension. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Depo-Provera injectable suspension if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Depo-Provera injectable suspension, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Depo-Provera injectable suspension.

Important safety information:

  • Depo-Provera injectable suspension may cause drowsiness, dizziness, lightheadedness, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Depo-Provera injectable suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Depo-Provera injectable suspension may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
  • Depo-Provera injectable suspension may cause a decrease in the amount of calcium in your bones. A decrease in bone calcium is of most concern if you have the following risk factors: adolescence, bone disease, anorexia nervosa (an eating disorder), a strong family history of osteoporosis, if you take certain medicines (eg, for epilepsy or steroids), or if you drink a lot of alcohol or smoke cigarettes often. When Depo-Provera injectable suspension is stopped, the calcium in bones begins to come back. Your health care provider may recommend that you take calcium or vitamin D to help lower the amount of calcium lost from your bones.
  • Diabetes patients - Depo-Provera injectable suspension may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Depo-Provera injectable suspension may interfere with certain lab tests, including urinary steroid levels, gonadotropin and other hormone levels, thyroid function, blood clotting tests, and blood cholesterol. Be sure your doctor and lab personnel know you are using Depo-Provera injectable suspension.
  • Lab tests, including blood calcium and bone density tests, may be performed while you use Depo-Provera injectable suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Depo-Provera injectable suspension should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Depo-Provera injectable suspension if you are pregnant. If you think you may be pregnant, contact your doctor right away. Depo-Provera injectable suspension is found in breast milk. If you are or will be breast-feeding while you use Depo-Provera injectable suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Depo-Provera injectable suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; dizziness; drowsiness; fever; headache; hot flashes; nausea; nervousness; pain, redness, and swelling at injection site; sleeplessness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood clots; changes in menstrual flow, including breakthrough bleeding, spotting, or missed periods; chest pain; mental or mood changes; partial or complete loss of vision or changes in vision; severe dizziness or fainting; severe stomach pain; shortness of breath; slurred speech; sudden loss of coordination; sudden or severe headache or vomiting; swelling of fingers or ankles; unusual weight gain or loss; weakness, numbness, or pain in the arms or legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Depo-Provera injectable suspension:

Store Depo-Provera injectable suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Depo-Provera injectable suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Depo-Provera injectable suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Depo-Provera injectable suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Depo-Provera injectable suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Depo-Provera injectable suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Depo-Provera injectable suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Depo-Provera injectable suspension.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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