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Cortisporin cream

Generic Name: hydrocortisone/neomycin/polymyxin b (HYE-droe-KOR-ti-sone/NEE-oh-MYE-sin/POL-ee-MIX-in)
Brand Name: Cortisporin

Cortisporin cream is used for:

Treating inflammation (swelling, warmth, redness, pain) due to certain skin conditions when an infection is present.

Cortisporin cream is a combination of 2 antibiotics and a corticosteroid. The antibiotics work by slowing the growth of, or killing, sensitive bacteria. The corticosteroid reduces inflammation.

Do NOT use Cortisporin cream if:

  • you are allergic to any ingredient in Cortisporin cream, to other aminoglycosides (eg, tobramycin), or to other corticosteroids (eg, prednisone)
  • you have a viral infection of the skin (eg, herpes simplex, vaccinia, chickenpox, shingles), tuberculosis of the skin, or a fungal skin infection
  • you are using Cortisporin cream on your ear and you have a perforated ear drum

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Cortisporin cream:

Some medical conditions may interact with Cortisporin cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have any kind of skin infection, cuts, scrapes, or lessened blood flow to your skin
  • if you have had a recent vaccination; have measles or tuberculosis; or you have had a positive tuberculosis test

Some MEDICINES MAY INTERACT with Cortisporin cream. Because little, if any, of Cortisporin cream is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Cortisporin cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cortisporin cream:

Use Cortisporin cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cortisporin cream is for topical use only. Do not get Cortisporin cream in your eyes. If you get Cortisporin cream in your eyes, rinse immediately with cool tap water.
  • Wash your hands before and after using Cortisporin cream.
  • Apply a small amount of medicine to the affected area. Rub in gently.
  • To clear up your infection completely, use Cortisporin cream for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Cortisporin cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cortisporin cream.

Important safety information:

  • Cortisporin cream only works against bacteria; it does not treat fungal or viral infections.
  • Be sure to use Cortisporin cream for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Cortisporin cream may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Do not use Cortisporin cream for other conditions at a later time.
  • Cortisporin cream has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Check with your doctor before having any vaccinations while you are using Cortisporin cream.
  • Cortisporin cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Cortisporin cream.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cortisporin cream while you are pregnant. It is not known if Cortisporin cream is found in breast milk after topical use. If you are or will be breast-feeding while you use Cortisporin cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Cortisporin cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning or peeling of the skin not present when you began using Cortisporin cream; changes in hearing; decreased urination; excessive hair growth; inflamed hair follicles; inflammation around the mouth; loss of hearing; muscle weakness; increased or persistent pain, redness, irritation, or swelling; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased thirst or urination; muscle weakness; unusual weight gain, especially in the face.

Proper storage of Cortisporin cream:

Store Cortisporin cream between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Keep Cortisporin cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Cortisporin cream, please talk with your doctor, pharmacist, or other health care provider.
  • Cortisporin cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Cortisporin cream or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cortisporin cream. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cortisporin cream. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Cortisporin cream.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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