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Cortane-B solution

Generic Name: chloroxylenol/hydrocortisone/pramoxine (klor-oh-ZYE-le-nole/HIGH-droe-CORE-tih-sone/pram-OX-een)
Brand Name: Examples include Cortane-B and Otozone

Cortane-B solution is used for:

Treating certain infections of the outer ear canal that are complicated by inflammation. It is also used to control itching of the ear canal.

Cortane-B solution is an antibacterial, steroid, and anesthetic combination. It works by killing bacteria, reducing inflammation, and temporarily relieving itching and pain.

Do NOT use Cortane-B solution if:

  • you are allergic to any ingredient in Cortane-B solution
  • you have chickenpox or vaccinia viral infection
  • your eardrum is perforated

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: View Frightful (But Dead Serious) Drug Side Effects

Before using Cortane-B solution:

Some medical conditions may interact with Cortane-B solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Cortane-B solution. Because little, if any, of Cortane-B solution is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Cortane-B solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cortane-B solution:

Use Cortane-B solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cortane-B solution is only for the ear. Do not get it in your eyes, nose, or mouth. If you get Cortane-B solution in the eyes, flush thoroughly with cool water.
  • Thoroughly clean and dry the outer ear before using Cortane-B solution.
  • Lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for 5 minutes so the medicine can run to the bottom of the ear canal. A clean cotton plug may be gently inserted into the ear canal to prevent medicine from leaking out.
  • To prevent germs from getting into your medicine, do not touch the applicator to any surface, including the ear. Keep the container tightly closed.
  • Wash your hands immediately after using Cortane-B solution.
  • If you miss a dose of Cortane-B solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cortane-B solution.

Important safety information:

  • Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Do not use Cortane-B solution for other conditions than the one for which it was prescribed.
  • Cortane-B solution may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Caution is advised when using Cortane-B solution in CHILDREN; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cortane-B solution while you are pregnant. It is not known if Cortane-B solution is found in breast milk. If you are or will be breast-feeding while you use Cortane-B solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Cortane-B solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning, cracking, irritation, or peeling not present before you began using Cortane-B solution; excessive hair growth; inflamed hair follicles; inflammation around the mouth; muscle weakness; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Cortane-B solution:

Store Cortane-B solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in the original container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cortane-B solution out of the reach of children and away from pets.

General information:

  • If you have any questions about Cortane-B solution, please talk with your doctor, pharmacist, or other health care provider.
  • Cortane-B solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Cortane-B solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cortane-B solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cortane-B solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Cortane-B solution.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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