Clindamycin solution

Pronunciation

Generic Name: clindamycin (KLIN-da-MYE-sin)
Brand Name: Cleocin

Mild diarrhea is common with antibiotic use. However, a severe form of diarrhea (Clostridium difficile-associated diarrhea) has been reported with nearly all antibiotics, including clindamycin solution. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.


Clindamycin solution is used for:

Treating serious infections caused by certain bacteria.

Clindamycin solution is a lincomycin antibiotic. It works by stopping the production of essential proteins needed by certain bacteria to survive.

Do NOT use clindamycin solution if:

  • you are allergic to any ingredient in clindamycin solution or to lincomycin
  • you have certain intestinal problems (eg, antibiotic-associated colitis, Crohn disease, ulcerative colitis) or meningitis

Contact your doctor or health care provider right away if any of these apply to you.

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Before using clindamycin solution:

Some medical conditions may interact with clindamycin solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea or a history of liver problems or stomach or bowel problems (eg, colitis)
  • if you have a decreased or lack of allergic response

Some MEDICINES MAY INTERACT with clindamycin solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Erythromycin because it may decrease clindamycin solution's effectiveness
  • Nondepolarizing muscle relaxants (eg, vecuronium) or succinylcholine because the risk of their side effects may be increased by clindamycin solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if clindamycin solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use clindamycin solution:

Use clindamycin solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Clindamycin solution is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using clindamycin solution at home, a health care provider will teach you how to use it. Be sure you understand how to use clindamycin solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use clindamycin solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Clindamycin solution works best if it is taken at the same time each day.
  • To clear up your infection completely, use clindamycin solution for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of clindamycin solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use clindamycin solution.

Important safety information:

  • Clindamycin solution only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use clindamycin solution for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of clindamycin solution may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use clindamycin solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use clindamycin solution with caution in the ELDERLY; they may be more sensitive to its effects, especially diarrhea.
  • Clindamycin solution has benzyl alcohol in it. Do not use it in NEWBORNS or INFANTS. It may cause serious and sometimes fatal nervous system problems and other side effects.
  • Use clindamycin solution with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using clindamycin solution while you are pregnant. Clindamycin solution is found in breast milk. If you are or will be breast-feeding while you use clindamycin solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of clindamycin solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild diarrhea; mild pain, swelling, or redness at the injection site; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or tarry stools; chest pain; decreased urination; dizziness; joint pain or swelling; fainting; numbness of an arm or leg; red, swollen, blistered, or peeling skin; severe or persistent diarrhea; severe nausea or vomiting; severe or persistent pain, redness, or swelling at the injection site; severe stomach pain or cramps; unusual vaginal discharge, itching, or odor; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of clindamycin solution:

Store clindamycin solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep clindamycin solution out of the reach of children and away from pets.

General information:

  • If you have any questions about clindamycin solution, please talk with your doctor, pharmacist, or other health care provider.
  • Clindamycin solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take clindamycin solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about clindamycin solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to clindamycin solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using clindamycin solution.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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