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Claforan

Generic Name: cefotaxime (SEF-oh-TAX-eem)
Brand Name: Claforan

Claforan is used for:

Treating infections caused by certain bacteria. It is also used to prevent bacterial infections before, during, or after certain surgeries.

Claforan is a cephalosporin antibiotic. It works by weakening and rupturing the cell wall, killing the bacteria.

Do NOT use Claforan if:

  • you are allergic to any ingredient in Claforan or to any other cephalosporin antibiotic (eg, cephalexin)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: The Shocking Truth About Antibiotic Resistance

Before using Claforan:

Some medical conditions may interact with Claforan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin (eg, amoxicillin) or other beta-lactam antibiotic (eg, imipenem)
  • if you have a history of stomach or bowel problems (eg, inflammation), blood clotting problems, or kidney or liver problems
  • if you have poor nutrition

Some MEDICINES MAY INTERACT with Claforan. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglycosides (eg, gentamicin) because the risk of kidney side effects may be increased
  • Probenecid because it may increase the risk of Claforan's side effects
  • Heparin because the risk of its side effects, including risk of bleeding, may be increased by Claforan

This may not be a complete list of all interactions that may occur. Ask your health care provider if Claforan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Claforan:

Use Claforan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Claforan is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Claforan at home, a health care provider will teach you how to use it. Be sure you understand how to use Claforan. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Claforan if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • To clear up your infection completely, use Claforan for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Claforan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Claforan.

Important safety information:

  • Claforan only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use Claforan for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Claforan may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Diabetes patients - Claforan may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
  • Claforan may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Claforan.
  • Lab tests, including kidney or liver tests or blood cell counts, may be performed while you use Claforan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Claforan with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Claforan while you are pregnant. Claforan is found in breast milk. If you are or will be breast-feeding while you use Claforan, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Claforan:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; mild diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody diarrhea or stools; decreased urination; fever, chills, or persistent sore throat; irregular heartbeat; pain, swelling, or redness at the injection site; red, swollen, or blistered skin; seizures; severe diarrhea; severe nausea or vomiting; stomach pain or cramps; unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; white patches in mouth; yellowing of the eyes and skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include seizures.

Proper storage of Claforan:

Claforan is usually handled and stored by a health care provider. If you are using Claforan at home, store Claforan as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Keep Claforan out of the reach of children and away from pets.

General information:

  • If you have any questions about Claforan, please talk with your doctor, pharmacist, or other health care provider.
  • Claforan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Claforan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Claforan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Claforan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Claforan.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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