Generic Name: chlorpheniramine/phenylephrine (klor-fen-IHR-ah-meen/fen-il-EF-rin)
Brand Name: Examples include Ny-Tannic and Rynatan
Chlorpheniramine/ phenylephrine is used for:
Relieving symptoms of sinus congestion, sinus pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.
Chlorpheniramine/phenylephrine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.
Do NOT use chlorpheniramine/ phenylephrine if:
- you are allergic to any ingredient in chlorpheniramine/phenylephrine
- you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
- you are taking sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using chlorpheniramine/ phenylephrine:
Some medical conditions may interact with chlorpheniramine/phenylephrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a fast, slow, or irregular heartbeat
- if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid
Some MEDICINES MAY INTERACT with chlorpheniramine/phenylephrine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of chlorpheniramine/phenylephrine's side effects
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by chlorpheniramine/phenylephrine
- Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by chlorpheniramine/phenylephrine
This may not be a complete list of all interactions that may occur. Ask your health care provider if chlorpheniramine/phenylephrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use chlorpheniramine/ phenylephrine:
Use chlorpheniramine/phenylephrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Chlorpheniramine/phenylephrine may be taken with or without food.
- If you miss a dose of chlorpheniramine/phenylephrine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use chlorpheniramine/phenylephrine.
Important safety information:
- Chlorpheniramine/phenylephrine may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to chlorpheniramine/phenylephrine. Using chlorpheniramine/phenylephrine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Do not take nonprescription medicines that contain stimulants, such as products used for dieting (appetite suppressants) without checking with you doctor.
- Do NOT exceed the recommended dose or take chlorpheniramine/phenylephrine for longer than prescribed without checking with your doctor.
- If your symptoms do not improve within 5 to 7 days or if they become worse, consult your doctor.
- Chlorpheniramine/phenylephrine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to chlorpheniramine/phenylephrine. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
- If you are scheduled for allergy skin testing, do not take chlorpheniramine/phenylephrine for several days before the test because it may decrease your response to the skin tests.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using chlorpheniramine/phenylephrine.
- Use chlorpheniramine/phenylephrine with caution in the ELDERLY because they may be more sensitive to its effects.
- Use chlorpheniramine/phenylephrine with caution in CHILDREN because they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking chlorpheniramine/phenylephrine, discuss with your doctor the benefits and risks of using chlorpheniramine/phenylephrine during pregnancy. It is unknown if chlorpheniramine/phenylephrine is excreted in breast milk. Do not breast-feed while taking chlorpheniramine/phenylephrine.
Possible side effects of chlorpheniramine/ phenylephrine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of chlorpheniramine/phenylephrine:
Store chlorpheniramine/phenylephrine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep chlorpheniramine/phenylephrine out of the reach of children and away from pets.
- If you have any questions about chlorpheniramine/phenylephrine, please talk with your doctor, pharmacist, or other health care provider.
- Chlorpheniramine/phenylephrine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take chlorpheniramine/phenylephrine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about chlorpheniramine/phenylephrine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to chlorpheniramine/phenylephrine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using chlorpheniramine/phenylephrine.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about chlorpheniramine/phenylephrine
- Chlorpheniramine/phenylephrine chewable tablets
- Chlorpheniramine/phenylephrine controlled-release tablets
- Chlorpheniramine/phenylephrine elixir
- Chlorpheniramine/phenylephrine suspension
- Chlorpheniramine/phenylephrine sustained-release capsules
- Chlorpheniramine and phenylephrine
- Phenylephrine and Chlorpheniramine Tablets (FDA)
- Phenylephrine Tannate/Chlorpheniramine Tannate (Wolters Kluwer)