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Chlorpheniramine/ guaifenesin/ phenylephrine drops

Generic Name: chlorpheniramine/guaifenesin/phenylephrine (klor-fen-EER-a-meen/gwye-FEN-e-sin/fen-ill-EF-rin)
Brand Name: Qual-Tussin Pediatric

Chlorpheniramine/ guaifenesin/ phenylephrine drops is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and throat and airway irritation due to colds, upper respiratory infections, and allergies. It may also be used for conditions as determined by your doctor.

Chlorpheniramine/guaifenesin/phenylephrine drops is a decongestant, antihistamine, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, making it easier to breathe. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing, while the expectorant loosens mucus and lung secretions in the chest and makes coughs more productive.

Do NOT use chlorpheniramine/ guaifenesin/ phenylephrine drops if:

  • you are allergic to any ingredient in chlorpheniramine/guaifenesin/phenylephrine drops
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are unable to urinate or are having an asthma attack
  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using chlorpheniramine/ guaifenesin/ phenylephrine drops:

Some medical conditions may interact with chlorpheniramine/guaifenesin/phenylephrine drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid

Some MEDICINES MAY INTERACT with chlorpheniramine/guaifenesin/phenylephrine drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of chlorpheniramine/guaifenesin/phenylephrine drops may be increased
  • Digoxin or droxidopa because risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by chlorpheniramine/guaifenesin/phenylephrine drops
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by chlorpheniramine/guaifenesin/phenylephrine drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if chlorpheniramine/guaifenesin/phenylephrine drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use chlorpheniramine/ guaifenesin/ phenylephrine drops:

Use chlorpheniramine/guaifenesin/phenylephrine drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Chlorpheniramine/guaifenesin/phenylephrine drops may be taken with or without food.
  • Use the dropper that comes with chlorpheniramine/guaifenesin/phenylephrine drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of chlorpheniramine/guaifenesin/phenylephrine drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use chlorpheniramine/guaifenesin/phenylephrine drops.

Important safety information:

  • Chlorpheniramine/guaifenesin/phenylephrine drops may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to chlorpheniramine/guaifenesin/phenylephrine drops. Using chlorpheniramine/guaifenesin/phenylephrine drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not take diet or appetite control medicines while you are taking chlorpheniramine/guaifenesin/phenylephrine drops without checking with your doctor.
  • Chlorpheniramine/guaifenesin/phenylephrine drops contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take chlorpheniramine/guaifenesin/phenylephrine drops for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
  • Chlorpheniramine/guaifenesin/phenylephrine drops may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to chlorpheniramine/guaifenesin/phenylephrine drops. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
  • If you are scheduled for allergy skin testing, do not take chlorpheniramine/guaifenesin/phenylephrine drops for several days before the test because it may decrease your response to the skin tests.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using chlorpheniramine/guaifenesin/phenylephrine drops.
  • Use chlorpheniramine/guaifenesin/phenylephrine drops with caution in the ELDERLY because they may be more sensitive to its effects.
  • Caution is advised when using chlorpheniramine/guaifenesin/phenylephrine drops in CHILDREN because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking chlorpheniramine/guaifenesin/phenylephrine drops, discuss with your doctor the benefits and risks of using chlorpheniramine/guaifenesin/phenylephrine drops during pregnancy. It is unknown if chlorpheniramine/guaifenesin/phenylephrine drops is excreted in breast milk. Do not breast-feed while taking chlorpheniramine/guaifenesin/phenylephrine drops.

Possible side effects of chlorpheniramine/ guaifenesin/ phenylephrine drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of chlorpheniramine/guaifenesin/phenylephrine drops:

Store chlorpheniramine/guaifenesin/phenylephrine drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep chlorpheniramine/guaifenesin/phenylephrine drops out of the reach of children and away from pets.

General information:

  • If you have any questions about chlorpheniramine/guaifenesin/phenylephrine drops, please talk with your doctor, pharmacist, or other health care provider.
  • Chlorpheniramine/guaifenesin/phenylephrine drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take chlorpheniramine/guaifenesin/phenylephrine drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about chlorpheniramine/guaifenesin/phenylephrine drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to chlorpheniramine/guaifenesin/phenylephrine drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using chlorpheniramine/guaifenesin/phenylephrine drops.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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