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Cefepime

Pronunciation

Generic Name: cefepime (SEF-e-peem)
Brand Name: Maxipime

Cefepime is used for:

Treating certain bacterial infections.

Cefepime is a cephalosporin antibiotic. It works by killing sensitive bacteria.

Do NOT use cefepime if:

  • you are allergic to any ingredient in cefepime or to another cephalosporin antibiotic (eg, cephalexin)
  • you have had a severe allergic reaction to a penicillin antibiotic (eg, amoxicillin) or another beta-lactam antibiotic (eg, imipenem)

Contact your doctor or health care provider right away if any of these apply to you.

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Before using cefepime:

Some medical conditions may interact with cefepime. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are allergic to penicillin antibiotics (eg, amoxicillin) or other beta-lactam antibiotics (eg, imipenem)
  • if you have stomach or bowel problems (eg, inflammation), blood clotting problems, kidney or liver problems, or poor nutrition

Some MEDICINES MAY INTERACT with cefepime. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglycosides (eg, gentamicin) or diuretics (eg, furosemide) because the risk of toxic effects on the kidneys may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if cefepime may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use cefepime:

Use cefepime as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cefepime is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using cefepime at home, a health care provider will teach you how to use it. Be sure you understand how to use cefepime. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use cefepime if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • To clear up your infection completely, use cefepime for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of cefepime, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use cefepime.

Important safety information:

  • Cefepime only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use cefepime for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of cefepime may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Cefepime may reduce the ability of your blood to clot. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Diabetes patients - Cefepime may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
  • There have been reports of nervous system problems (eg, fainting, confusion, hallucinations, coma, seizures) in some patients who take cefepime. Talk to your doctor if you develop any of these symptoms or if you have any questions or concerns.
  • Cefepime may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using cefepime.
  • Use cefepime with caution in the ELDERLY; they may be more sensitive to its effects.
  • Use cefepime with extreme caution in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using cefepime while you are pregnant. Cefepime is found in breast milk. If you are or will be breast-feeding while you use cefepime, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of cefepime:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild diarrhea; mild pain, redness, or swelling at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; fainting; fever, chills, or persistent sore throat; hallucinations; muscle twitching; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea, nausea, or vomiting; severe pain, redness, or swelling at the injection site; sluggishness; stomach pain or cramps; unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; white patches in the mouth; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; hallucinations; muscle twitching; seizures; sluggishness.

Proper storage of cefepime:

Cefepime is usually handled and stored by a health care provider. If you are using cefepime at home, store cefepime as directed by your pharmacist or health care provider. Keep cefepime out of the reach of children and away from pets.

General information:

  • If you have any questions about cefepime, please talk with your doctor, pharmacist, or other health care provider.
  • Cefepime is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take cefepime or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about cefepime. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to cefepime. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using cefepime.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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