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Brevibloc

Generic Name: esmolol (ES-moe-lol)
Brand Name: Brevibloc

Brevibloc is used for:

Temporary control of heart rate and blood pressure. It may also be used for other conditions as determined by your doctor.

Brevibloc is a beta-blocker. It works by reducing the workload on the heart and helping the heart beat more regularly.

Do NOT use Brevibloc if:

  • you are allergic to any ingredient in Brevibloc
  • you have heart block, shock caused by serious heart problems, moderate to severe heart failure, certain types of irregular heartbeat (eg, sick sinus syndrome), a very slow heartbeat, or pulmonary hypertension
  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brevibloc:

Some medical conditions may interact with Brevibloc. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had an allergic reaction to another beta-blocker (eg, metoprolol)
  • if you have heart problems (eg, heart blood vessel problems, heart failure, irregular heartbeat), chest pain (angina), blood flow problems, kidney problems, low blood volume, lung or breathing problems (eg, asthma, chronic obstructive pulmonary disorder [COPD]), diabetes, an overactive thyroid, or an adrenal gland tumor (pheochromocytoma)
  • if you have a history of low blood sugar

Some MEDICINES MAY INTERACT with Brevibloc. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Insulin or other diabetes medicines because the risk of low blood sugar may be increased
  • Clonidine, guanfacine, or moxonidine because stopping any of these medicines suddenly can lead to a rapid increase in blood pressure
  • Diltiazem, fingolimod, flecainide, mefloquine, mibefradil, or verapamil because the risk of serious heart problems may be increased
  • Indomethacin because it may decrease Brevibloc's effectiveness
  • Alfuzosin, digoxin, or prazosin because the risk of their side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brevibloc may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brevibloc:

Use Brevibloc as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Brevibloc is usually given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • If you miss a dose of Brevibloc, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Brevibloc.

Important safety information:

  • Brevibloc may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Brevibloc with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Tell your doctor or dentist that you take Brevibloc before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Brevibloc may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies also may not work as well while you are using Brevibloc.
  • Lab tests, including blood electrolyte levels and blood pressure, may be performed while you use Brevibloc. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Brevibloc should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brevibloc while you are pregnant. It is not known if Brevibloc is found in breast milk. Do not breast-feed while taking Brevibloc.

Possible side effects of Brevibloc:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); chest, jaw, or arm pain; confusion; fainting; irregular or unusually slow heartbeat; light-headedness; mental or mood changes; pain, irritation, blisters, redness, or swelling at the injection site; seizures; severe or persistent dizziness; shortness of breath; sudden, severe nausea or vomiting; unusual sweating or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness and weakness, especially upon standing; severe chest pain; slowed heartbeat.

Proper storage of Brevibloc:

Brevibloc is usually handled and stored by a health care provider. If you are using Brevibloc at home, store Brevibloc as directed by your pharmacist or health care provider. Keep Brevibloc out of the reach of children and away from pets.

General information:

  • If you have any questions about Brevibloc, please talk with your doctor, pharmacist, or other health care provider.
  • Brevibloc is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Brevibloc or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Brevibloc. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Brevibloc. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Brevibloc.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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