Biclora

Generic Name: chlophedianol/chlorcyclizine (KLOE-fe-DYE-a-nol/klor-SYE-klih-zeen)
Brand Name: Biclora

Biclora is used for:

Relieving cough and other symptoms, such as runny nose, sneezing, itchy nose or throat, and itchy or watery eyes, due to colds, hay fever, or allergies. It may also be used for other conditions as determined by your doctor.

Biclora is an antihistamine and cough suppressant combination. The antihistamine works by blocking histamine, which reduces allergy symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Biclora if:

  • you are allergic to any ingredient in Biclora
  • you are unable to urinate or are having an asthma attack
  • you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Biclora:

Some medical conditions may interact with Biclora. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of adrenal gland problems (eg, Addison disease); heart problems (eg, fast, slow, or irregular heartbeat); high blood pressure; heart blood vessel problems; a stroke; glaucoma or increased pressure in the eyes; seizures; or an overactive thyroid
  • if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea); if you have a chronic cough; or if your cough occurs with large amounts of mucus
  • if you have a blockage of your bladder, stomach, or bowels; ulcers; an enlarged prostate or other prostate problems; or trouble urinating

Some MEDICINES MAY INTERACT with Biclora. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Furazolidone, linezolid, MAOIs (eg, phenelzine), or sodium oxybate (GHB) because they may increase the risk of Biclora's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Biclora may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Biclora:

Use Biclora as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Biclora by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • If you miss a dose of Biclora and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Biclora.

Important safety information:

  • Biclora may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Biclora with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Biclora; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not drink alcohol while you are taking Biclora.
  • Biclora has an antihistamine and a cough suppressant in it. Before you start any new medicine, check the label to see if it has an antihistamine and a cough suppressant in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take Biclora for longer than prescribed without checking with your doctor.
  • If new symptoms occur, or if cough persists for more than 1 week; goes away and comes back; or is accompanied by a fever, rash, or persistent headache, check with your doctor.
  • Do not use Biclora for a cough with a lot of mucus. Do not use for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Biclora may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Biclora. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Biclora may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Biclora for a few days before the tests.
  • Tell your doctor or dentist that you take Biclora before you receive any medical or dental care, emergency care, or surgery.
  • Use Biclora with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.
  • Caution is advised when using Biclora in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Biclora should not be used in CHILDREN younger than 6 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Biclora while you are pregnant. It is not known if Biclora is found in breast milk. If you are or will be breast-feeding while you take Biclora, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Biclora:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, light-headedness, or headache; tremor; trouble sleeping; vision changes (eg, blurred vision).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Biclora:

Store Biclora at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Biclora out of the reach of children and away from pets.

General information:

  • If you have any questions about Biclora, please talk with your doctor, pharmacist, or other health care provider.
  • Biclora is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Biclora or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Biclora. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Biclora. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Biclora.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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