Generic Name: pseudoephedrine/chlorcyclizine/chlophedianol (SOO-doe-e-FED-rin/klor-SYE-klih-zeen/KLOE-fe-DYE-a-nol)
Brand Name: Biclora-D
Biclora-D is used for:
Relieving symptoms of sinus congestion, runny nose, sneezing, itchy nose or throat, itchy or watery eyes, and cough due to colds, hay fever, and other upper respiratory allergies. It may also be used for other conditions as determined by your doctor.
Biclora-D is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce dry cough.
Do NOT use Biclora-D if:
- you are allergic to any ingredient in Biclora-D
- you have severe or uncontrolled high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
- you are unable to urinate or are having an asthma attack
- you are taking droxidopa or sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using Biclora-D:
Some medical conditions may interact with Biclora-D. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems (eg, fast, slow, or irregular heartbeat; heart disease), high or low blood pressure, low blood volume, diabetes, blood vessel problems, stroke, glaucoma or increased pressure in the eye, seizures, mental or mood problems (eg, depression), thyroid problems, or trouble sleeping
- if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea); chronic cough; or your cough occurs with large amounts of mucus
- if you have a history of stomach or bowel ulcers; a blockage of your stomach, bladder, or bowels; an enlarged prostate or other prostate problems; kidney problems; or trouble urinating
- if you take medicine for high blood pressure or depression
Some MEDICINES MAY INTERACT with Biclora-D. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Beta-blockers (eg, propranolol), furazolidone, linezolid, MAOIs (eg, phenelzine), selective serotonin reuptake inhibitors (SSRIs) (eg, citalopram, fluoxetine), sodium oxybate (GHB), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Biclora-D's side effects
- Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Biclora-D
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Biclora-D
This may not be a complete list of all interactions that may occur. Ask your health care provider if Biclora-D may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Biclora-D:
Use Biclora-D as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Biclora-D by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Take Biclora-D with a full glass of water (8 oz/240 mL).
- If you miss a dose of Biclora-D and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Biclora-D.
Important safety information:
- Biclora-D may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Biclora-D with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol while you are using Biclora-D.
- Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Biclora-D; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do not take diet or appetite control medicines while you take Biclora-D without checking with your doctor.
- Biclora-D has a decongestant, antihistamine, and cough suppressant in it. Before you start any new medicine, check the label to see if it has a decongestant, antihistamine, or cough suppressant in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Do not use Biclora-D for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
- Do NOT take more than the recommended dose or use for longer than recommended without checking with your doctor.
- If new symptoms occur or if cough or nasal congestion persists for more than 1 week, goes away and returns, or occurs along with a fever, rash, or persistent headache, check with your doctor. A persistent cough could be a sign of a serious condition.
- Biclora-D may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Biclora-D. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Biclora-D may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Biclora-D for a few days before the tests.
- Tell your doctor or dentist that you take Biclora-D before you receive any medical or dental care, emergency care, or surgery.
- Use Biclora-D with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, nervousness, sleeplessness, and trouble urinating.
- Caution is advised when using Biclora-D in CHILDREN; they may be more sensitive to its effects, especially excitability.
- Biclora-D should not be used in CHILDREN younger than 6 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Biclora-D while you are pregnant. Some ingredients of Biclora-D are found in breast milk. Do not breast-feed while taking Biclora-D.
Possible side effects of Biclora-D:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Anxiety; constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; increased sweating; loss of appetite; nausea; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or persistent sore throat; flushing or redness of the face; hallucinations; loss of coordination; mental or mood changes (eg depression, nervousness); numbness or tingling; seizures; severe dryness of the mouth, nose, or throat; severe or persistent dizziness, drowsiness, light-headedness, or headache; severe or persistent trouble sleeping; shortness of breath; tremor; unusual bruising or bleeding; unusual tiredness or weakness; vision problems (eg, double vision, blurred vision).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; flushing; hallucinations; mental or mood changes; muscle spasms; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; trouble breathing; unusual eye movements; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of Biclora-D:
Store Biclora-D at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Biclora-D out of the reach of children and away from pets.
- If you have any questions about Biclora-D, please talk with your doctor, pharmacist, or other health care provider.
- Biclora-D is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Biclora-D or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Biclora-D. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Biclora-D. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Biclora-D.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.