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Amantadine syrup

Pronunciation

Generic Name: amantadine (a-MAN-ta-deen)
Brand Name: Generic only. No brands available.

Amantadine syrup is used for:

Preventing and treating certain types of flu. It is used to treat Parkinson disease and uncontrolled muscle movements caused by some medicines. It may also be used for other conditions as determined by your doctor.

Amantadine syrup is an antiparkinson and antiviral agent. How amantadine syrup works against the flu is not known. It may block reproduction of the virus and decrease the ability of the virus to get into the cells. How amantadine syrup works against Parkinson disease is not known. It may increase a certain chemical in the brain.

Do NOT use amantadine syrup if:

  • you are allergic to any ingredient in amantadine syrup
  • you have uncontrolled narrow-angle glaucoma

Contact your doctor or health care provider right away if any of these apply to you.

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Before using amantadine syrup:

Some medical conditions may interact with amantadine syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems (eg, congestive heart failure), swelling of your hands or feet, mental or mood problems, suicidal thoughts or actions, seizures, glaucoma, low blood pressure, dizziness when you stand or sit up, an eczema-like rash, or kidney or liver problems
  • if you have received an intranasal flu vaccine within the last 14 days

Some MEDICINES MAY INTERACT with amantadine syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Thioridazine because tremors may be worsened in Parkinson patients
  • Anticholinergics (eg, scopolamine), hydrochlorothiazide, quinidine, quinine, stimulants (eg, caffeine, methylphenidate, pseudoephedrine), or triamterene because they may increase the risk of amantadine syrup's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if amantadine syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use amantadine syrup:

Use amantadine syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take amantadine syrup by mouth with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you are using amantadine syrup for the flu, take it for the full course of treatment. Keep using amantadine syrup even if you feel better in a few days. This will help clear up your infection completely.
  • If you miss a dose of amantadine syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use amantadine syrup.

Important safety information:

  • Amantadine syrup may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use amantadine syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Amantadine syrup may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Limit alcohol intake while you are taking amantadine syrup. Talk with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using amantadine syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Amantadine syrup only works against certain types of the flu; it does not treat other viral infections (eg, the common cold).
  • If you are taking amantadine syrup for the flu, be sure to use amantadine syrup for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The virus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • You usually should not receive a live nasal flu vaccine within 14 days before or 2 days after you take amantadine syrup. The vaccine may not work as well. Talk with your doctor before you receive any vaccine.
  • If you are taking amantadine syrup for Parkinson disease, increase physical activity slowly as your symptoms improve.
  • Do not suddenly stop taking amantadine syrup without first checking with your doctor. Your dose may need to be lowered slowly to avoid side effects.
  • Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by amantadine syrup. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
  • If your symptoms do not get better or if they get worse, check with your doctor.
  • Use amantadine syrup with caution in the ELDERLY; they may be more sensitive to its effects.
  • Amantadine syrup should be used with extreme caution in CHILDREN younger than 1 year old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using amantadine syrup while you are pregnant. Amantadine syrup is found in breast milk. Do not breast-feed while taking amantadine syrup.

If you stop taking amantadine syrup suddenly, you may have WITHDRAWAL symptoms. These may include agitation, hallucinations, paranoia, anxiety, depression, confusion, or slurred speech.

Possible side effects of amantadine syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; blurred vision; constipation; diarrhea; dizziness; drowsiness; dry mouth or nose; headache; lightheadedness; nausea; strange dreams; tiredness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggression; agitation; confusion; depression; fainting; fast or irregular heartbeat; fever; hallucinations; memory loss; mental or mood changes; muscle problems (eg, spasms, uncontrolled movements); paranoid thoughts; personality changes; seizures; severe or persistent drowsiness or trouble sleeping; shortness of breath; swelling of hands, legs, feet, or ankles; thoughts of suicide; trouble urinating; unusual anxiety or irritability; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include aggression; chest pain; confusion; decreased urination; fast or irregular heartbeat; fever; hallucinations; loss of consciousness; mental or mood changes; seizures; severe drowsiness; severe or persistent headache or dizziness; tremor; trouble breathing; trouble walking. Overdose of amantadine syrup may cause death.

Proper storage of amantadine syrup:

Store amantadine syrup at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep amantadine syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about amantadine syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Amantadine syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take amantadine syrup or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about amantadine syrup. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to amantadine syrup. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using amantadine syrup.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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