Have severe COPD? Learn how to manage your symptoms.

Alpha1-proteinase inhibitor (human)

Generic Name: alpha-1 proteinase inhibitor (human) (AL-fa PROE-teen-ase in-HIB-i-ter)
Brand Name: Examples include Aralast NP and Zemaira

Alpha1-proteinase inhibitor (human) is used for:

Treating emphysema caused by alpha-1 proteinase inhibitor deficiency (also known as alpha-1 antitrypsin deficiency).

Alpha1-proteinase inhibitor (human) is an alpha-1 protease inhibitor. It works by blocking substances in the lungs that break down lung tissue and sometimes causes emphysema.

Do NOT use alpha1-proteinase inhibitor (human) if:

  • you are allergic to any ingredient in alpha1-proteinase inhibitor (human)
  • you have an immunoglobulin A (IgA) deficiency and have antibodies against IgA

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Aging Eyes - 8 Common Vision Problems Associated with Aging

Before using alpha1-proteinase inhibitor (human):

Some medical conditions may interact with alpha1-proteinase inhibitor (human). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart or circulatory problems

Some MEDICINES MAY INTERACT with alpha1-proteinase inhibitor (human). However, no specific interactions with alpha1-proteinase inhibitor (human) are known at this time.

Ask your health care provider if alpha1-proteinase inhibitor (human) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use alpha1-proteinase inhibitor (human):

Use alpha1-proteinase inhibitor (human) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Alpha1-proteinase inhibitor (human) is administered as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • Do not miss any doses. If you miss a dose of alpha1-proteinase inhibitor (human), contact your doctor.

Ask your health care provider any questions you may have about how to use alpha1-proteinase inhibitor (human).

Important safety information:

  • Tell your doctor or dentist that you take alpha1-proteinase inhibitor (human) before you receive any medical or dental care, emergency care, or surgery.
  • Alpha1-proteinase inhibitor (human) contains albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used alpha1-proteinase inhibitor (human).
  • PREGNANCY and BREAST-FEEDING: It is not known if alpha1-proteinase inhibitor (human) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using alpha1-proteinase inhibitor (human) while you are pregnant. It is not known if alpha1-proteinase inhibitor (human) is excreted in breast milk. If you are or will be breast-feeding while you use alpha1-proteinase inhibitor (human), check with your doctor. Discuss any possible risks to your baby.

Possible side effects of alpha1-proteinase inhibitor (human):

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; muscle pain; nausea; pain, bruising, swelling, or redness at the injection site; runny nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; severe or persistent dizziness; shortness of breath or wheezing; swelling of the ankles or feet; symptoms of infection (eg, fever, chills, muscle aches, sore throat); tingling or numbness of the skin; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of alpha1-proteinase inhibitor (human):

Alpha1-proteinase inhibitor (human) is handled and stored by a health care provider. You will not store it at home. Keep all medicines, as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about alpha1-proteinase inhibitor (human), please talk with your doctor, pharmacist, or other health care provider.
  • Alpha1-proteinase inhibitor (human) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take alpha1-proteinase inhibitor (human) or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about alpha1-proteinase inhibitor (human). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to alpha1-proteinase inhibitor (human). This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using alpha1-proteinase inhibitor (human).

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Hide
(web3)