Generic Name: alogliptin (AL-oh-GLIP-tin)
Brand Name: Nesina
Alogliptin is used for:
Treating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.
Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the amount of insulin released by your body and decreasing the amount of sugar made by your body.
Do NOT use alogliptin if:
- you are allergic to any ingredient in alogliptin
- you have type 1 diabetes
- you have high blood ketone levels (diabetic ketoacidosis)
Contact your doctor or health care provider right away if any of these apply to you.
Before using alogliptin:
Some medical conditions may interact with alogliptin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) caused by another DPP-4 inhibitor (eg, saxagliptin)
- if you have a history of inflammation of the pancreas (pancreatitis), stones in your gallbladder (gallstones), or kidney or liver problems, or if you are receiving dialysis
- if you drink alcohol or have a history of alcohol abuse
Some MEDICINES MAY INTERACT with alogliptin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Insulin, meglitinides (eg, repaglinide), or sulfonylureas (eg, glipizide) because the risk of low blood sugar may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if alogliptin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use alogliptin:
Use alogliptin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Alogliptin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get alogliptin refilled.
- Take alogliptin by mouth with or without food.
- Take alogliptin on a regular schedule to get the most benefit from it.
- Continue to take alogliptin even if you feel well. Do not miss any doses.
- If you miss a dose of alogliptin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use alogliptin.
Important safety information:
- Follow the diet and exercise program given to you by your health care provider. Proper diet, regular exercise, and regular blood sugar testing are important for best results with alogliptin.
- Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take alogliptin exactly as prescribed, tell your doctor.
- It may be harder to control your blood sugar during times of stress such as fever, infection, injury, or surgery. Talk with your doctor about how to control your blood sugar if any of these occur. Do not change the dose of your medicine without checking with your doctor.
- Alogliptin usually does not cause low blood sugar. However, low blood sugar may occur when it is used along with certain other medicines for diabetes (eg, insulin, sulfonylureas). Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or nondiet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.
- Severe and sometimes fatal liver problems have been reported in patients taking alogliptin. Call your doctor right away if you have symptoms of liver problems (eg, dark urine; stomach pain; unexplained nausea, vomiting, or loss of appetite; yellowing of the skin or eyes). Discuss any questions or concerns with your doctor.
- Severe and sometimes fatal inflammation of the pancreas (pancreatitis) has been reported in patients taking alogliptin. Discuss any questions or concerns with your doctor. Contact your doctor immediately if you develop severe or persistent stomach or back pain with or without nausea or vomiting.
- Lab tests, including kidney and liver function, fasting blood glucose, and hemoglobin A1c, may be performed while you use alogliptin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Alogliptin should be used with extreme caution in CHILDREN; safety and effectiveness in these children have not been confirmed.
- PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking alogliptin while you are pregnant. It is not known if alogliptin is found in breast milk. If you are or will be breast-feeding while you take alogliptin, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of alogliptin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Cold-like symptoms; headache; runny or stuffy nose; sore throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); red, swollen, blistered, or peeling skin; symptoms of pancreas inflammation (eg, severe stomach or back pain with or without nausea or vomiting).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of alogliptin:
Store alogliptin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep alogliptin out of the reach of children and away from pets.
- If you have any questions about alogliptin, please talk with your doctor, pharmacist, or other health care provider.
- Alogliptin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take alogliptin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about alogliptin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to alogliptin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using alogliptin.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about alogliptin
- Other brands: Nesina