Tranylcypromine use while Breastfeeding

Drugs containing Tranylcypromine: Parnate

Tranylcypromine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because of the lack of data on use during breastfeeding, other antidepressants are preferred during breastfeeding.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Nine subjects were treated with an average dose of 29 mg daily (range10 to 40 mg) of oral tranylcypromine day for an average of 16 days. Serum prolactin levels increased by 3 mcg/L.[1]The clinical relevance of these findings in nursing mothers is not known. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs to Consider

Nortriptyline, Paroxetine, Sertraline

References

1. Price LH, Charney DS, Heninger GR. Effects of tranylcypromine treatment on neuroendocrine, behavioral, and autonomic responses to tryptophan in depressed patients. Life Sci. 1985;37:809-18. PMID: 4033356

Tranylcypromine Identification

Substance Name

Tranylcypromine

CAS Registry Number

155-09-9

Drug Class

Administrative Information

LactMed Record Number

311

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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