Tocainide use while Breastfeeding
Drugs containing Tocainide: Tonocard
Tocainide Levels and Effects while Breastfeeding
Summary of Use during Lactation
Limited data indicate that rather large amounts of tocainide are excreted into breastmilk. Because of the relative lack of data concerning breastfeeding during maternal tocainide therapy, exclusively breastfed infants should be carefully monitored if this drug is used during lactation, possibly including measurement of serum levels to rule out toxicity if there is a concern.
Drug Levels
Maternal Levels. One woman taking tocainide 400 mg every 8 hours orally during the early postpartum period had levels of 12 mg/L at 0.5 hour before a dose and 28 mg/L at 2 hours after a dose.[1] These data indicate that an exclusively breastfed infant would receive between 9 and 21% of the maternal weight-adjusted dosage.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
References
1. Wilson JH. Breast milk tocainide levels. J Cardiovasc Pharmacol. 1988;12:497. Letter. PMID: 2465453
Tocainide Identification
Substance Name
CAS Registry Number
41708-72-9
Drug Class
- Antiarrhythmics
Administrative Information
LactMed Record Number
260
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2011-01-04
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Tocainide use during Pregnancy
- Tocainide Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
